{"id":"W3167248437","doi":"10.1371/journal.pgen.1009146","title":"Crumbs and the apical spectrin cytoskeleton regulate R8 cell fate in the Drosophila eye","year":2021,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; National Health and Medical Research Council; Medical Research Council; Peter MacCallum Foundation; Australian Research Council; Australian Cancer Research Foundation","keywords":"Biology; Hippo signaling pathway; Cell biology; Cell fate determination; Drosophila melanogaster; Mitosis; Signal transduction; Genetics; Transcription factor; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002850956,0.0001611738,0.0001656645,0.00001977507,0.0001087373,0.00006319502,0.0002548,0.0001468316,0.00001328595],"category_scores_gemma":[0.00006609408,0.0001051646,0.00008264415,0.0001262191,0.0001757652,0.000001270621,0.0001344649,0.0001973949,0.00001347132],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006910283,"about_ca_system_score_gemma":0.00006462046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003712548,"about_ca_topic_score_gemma":0.00002484883,"domain_scores_codex":[0.9986942,0.0002782374,0.0002198913,0.0003455241,0.0001888717,0.0002732974],"domain_scores_gemma":[0.9992679,0.00004761961,0.00005408889,0.0005225868,0.00005212282,0.00005562015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004893137,0.00009037975,0.001109397,0.00002181502,0.00002345371,0.00002962458,0.0003271909,0.00009802278,0.997593,0.0002509724,0.00009258348,0.0003146446],"study_design_scores_gemma":[0.001249541,0.0001091455,0.001301691,0.00001600938,0.00004340006,0.00002405243,0.0001693864,0.001068624,0.9861615,0.001085955,0.008585573,0.000185136],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913755,0.00483346,0.00006435823,0.001613627,0.00006569923,0.0001813698,0.00001130602,0.000008029925,0.001846652],"genre_scores_gemma":[0.9968554,0.001152362,0.0002687543,0.0006832039,0.0003137731,0.00001844254,0.00003614652,0.0000222376,0.000649631],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0114315,"threshold_uncertainty_score":0.4288488,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01017088262059319,"score_gpt":0.2214368777411482,"score_spread":0.2112659951205551,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}