{"id":"W3167307886","doi":"10.1096/fasebj.2021.35.s1.00054","title":"Protective Roles of O‐GlcNAc in Neurodegenerative Diseases","year":2021,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Alzheimer Society","keywords":"Neurodegeneration; Biochemistry; Oxidative stress; Glycosyltransferase; Genetically modified mouse; Cytosol; Glycation; Enzyme; Glycobiology; Biology; Transgene; Chemistry; Cell biology; Disease; Gene; Medicine; Internal medicine; Glycoprotein; Receptor; Glycan","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002585548,0.0005554159,0.0004609683,0.0003826589,0.0002365971,0.0005678659,0.0003953149,0.0005918265,0.00154003],"category_scores_gemma":[0.0001922163,0.0001278807,0.0003085377,0.000295652,0.0003006685,0.0008018371,0.000493688,0.001146725,0.000662052],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003699973,"about_ca_system_score_gemma":0.000429956,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004036722,"about_ca_topic_score_gemma":0.000614334,"domain_scores_codex":[0.9999229,0.00001315441,0.000006169549,0.00001540834,0.00002111515,0.00002127903],"domain_scores_gemma":[0.999911,0.00001015967,0.00002393559,0.000005859933,0.00002396456,0.00002505894],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001356981,0.0004516234,0.001592418,0.005424569,0.0001575694,0.0007673437,0.0002238466,0.0008946831,0.6970063,0.01136556,0.009963816,0.2707952],"study_design_scores_gemma":[0.0001628156,0.002532904,0.0153819,0.0008291335,0.0004690147,0.002811193,0.0002683966,0.002038478,0.5266122,0.01070116,0.4380679,0.0001248953],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.08181573,0.8954726,0.006956344,0.002894862,0.001159613,0.00006776013,0.0004764132,0.0003439158,0.01081273],"genre_scores_gemma":[0.3116158,0.6680237,0.006363335,0.001956415,0.001192907,0.0000979347,0.0008081709,0.00006954857,0.009872085],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00154003,"threshold_uncertainty_score":0.005151927,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01320351420382639,"score_gpt":0.2719229433694101,"score_spread":0.2587194291655838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}