{"id":"W3167351821","doi":"10.1096/fasebj.2021.35.s1.03058","title":"MicroRNA miR‐378‐3p is an Essential Regulator of Autophagy and Proliferation in Endothelial Cells","year":2021,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Autophagy; Cell biology; Gene silencing; microRNA; Downregulation and upregulation; Lysosome; PI3K/AKT/mTOR pathway; Biology; Regulator; Chemistry; Signal transduction; Biochemistry; Apoptosis; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001358958,0.0002892927,0.0003232608,0.0002423225,0.0002798956,0.0002669203,0.0002019568,0.000210619,0.001150052],"category_scores_gemma":[0.0001845986,0.0001419972,0.0002833234,0.0001701933,0.0001690778,0.000129918,0.0001540982,0.0003735892,0.0004905429],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004979831,"about_ca_system_score_gemma":0.000380375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005323292,"about_ca_topic_score_gemma":0.000549788,"domain_scores_codex":[0.9998031,0.00002326143,0.00002390263,0.00004577274,0.00007355553,0.00003036641],"domain_scores_gemma":[0.9998848,0.0000166588,0.00003330075,0.0000108306,0.00003192043,0.00002240998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002368676,0.00002574269,0.0005271782,0.00007252957,0.000009318956,0.0001410986,0.00001721992,0.00009854092,0.9956321,0.0002717609,0.0002648792,0.002702745],"study_design_scores_gemma":[0.00002587729,0.0002011012,0.009368011,0.00001672846,0.00003397563,0.0006471958,0.00003208115,0.001872854,0.9760422,0.0002711385,0.01147763,0.00001125528],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9622056,0.01257435,0.01242708,0.0004155104,0.0002487867,0.000106269,0.0030419,0.0007010646,0.008279382],"genre_scores_gemma":[0.9892129,0.0014817,0.004876306,0.0001322489,0.00002923951,0.0001386848,0.00126812,0.00004545267,0.002815471],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001150052,"threshold_uncertainty_score":0.003847301,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01243900506264506,"score_gpt":0.2665839374816841,"score_spread":0.2541449324190391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}