{"id":"W3167734456","doi":"10.1039/d1fo00693b","title":"Structure–activity relationship of avocadyne","year":2021,"lang":"en","type":"article","venue":"Food & Function","topic":"Plant Physiology and Cultivation Studies","field":"Agricultural and Biological Sciences","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Regional Municipality of Waterloo; University of Waterloo; Toronto Public Health; Ontario Institute for Cancer Research; Centennial College; IONICS Mass Spectrometry (Canada); Alberta Hospital Edmonton; University of Alberta; University of Guelph","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Cancer Research Society","keywords":"Acetogenin; In vitro; Fatty acid; Chemistry; In vivo; Structure–activity relationship; Stereochemistry; Chemical structure; Biochemistry; Biology; Organic chemistry; Genetics; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009604579,0.0002454153,0.0001802453,0.0002879677,0.00009691623,0.0002414859,0.0001794388,0.0001750924,0.002654888],"category_scores_gemma":[0.0001725875,0.00006768241,0.0002556077,0.0002150204,0.0001115373,0.0001675728,0.0001334807,0.0003189232,0.0004024165],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001795283,"about_ca_system_score_gemma":0.0001693573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00122373,"about_ca_topic_score_gemma":0.001594182,"domain_scores_codex":[0.9999436,0.00001219864,0.00000491989,0.00001235388,0.00001028123,0.00001670104],"domain_scores_gemma":[0.9999056,0.00002301336,0.00001695186,0.000006436457,0.0000187772,0.00002922316],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001099371,0.0002313698,0.000646818,0.0001717828,0.00003079613,0.0001056016,0.00002230917,0.0008974139,0.9872958,0.0002135147,0.0001745685,0.009110548],"study_design_scores_gemma":[0.0001438132,0.01169959,0.01265429,0.0000322178,0.0001157334,0.000393425,0.00007637958,0.001991322,0.9592353,0.0002169069,0.01340987,0.0000310164],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9792476,0.01140465,0.001586624,0.000137262,0.00005635467,0.00007185169,0.001252574,0.00004101903,0.006202077],"genre_scores_gemma":[0.9927602,0.00253037,0.0007726662,0.00007210115,0.00001552486,0.0000136772,0.0008626461,0.000005577125,0.002967352],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002654888,"threshold_uncertainty_score":0.00888145,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03761865417810292,"score_gpt":0.2074037715267472,"score_spread":0.1697851173486442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}