{"id":"W3167734456","doi":"10.1039/d1fo00693b","title":"Structure–activity relationship of avocadyne","year":2021,"lang":"en","type":"article","venue":"Food & Function","topic":"Plant Physiology and Cultivation Studies","field":"Agricultural and Biological Sciences","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Regional Municipality of Waterloo; University of Waterloo; Toronto Public Health; Ontario Institute for Cancer Research; Centennial College; IONICS Mass Spectrometry (Canada); Alberta Hospital Edmonton; University of Alberta; University of Guelph","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Cancer Research Society","keywords":"Acetogenin; In vitro; Fatty acid; Chemistry; In vivo; Structure–activity relationship; Stereochemistry; Chemical structure; Biochemistry; Biology; Organic chemistry; Genetics; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003607043,0.00004502156,0.00007637493,0.000003561824,0.0001301305,0.000004223058,0.00002485917,0.00005349647,0.0002526819],"category_scores_gemma":[0.00007017709,0.00001793657,0.00003451436,0.0001814795,0.00002133698,0.00007089454,0.00001715129,0.00006411986,0.000009457532],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004826156,"about_ca_system_score_gemma":0.000004261122,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007413607,"about_ca_topic_score_gemma":0.0002045767,"domain_scores_codex":[0.9996374,0.00005132312,0.00007303577,0.0001100616,0.00006541476,0.00006271134],"domain_scores_gemma":[0.999698,0.0001382975,0.00005407318,0.0000243478,0.00007170689,0.00001355257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002884471,0.00004034676,0.03335714,0.000003722817,0.00002948018,2.360763e-7,0.00002474185,0.000008319222,0.953423,0.002917692,0.0002245634,0.009682269],"study_design_scores_gemma":[0.00005138797,0.0007354057,0.9740835,0.000003887688,0.00001034626,0.000001828423,0.00009554359,0.0000035231,0.01935781,0.003451285,0.002162921,0.00004259169],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984233,0.00009833134,0.00001860164,0.0002552932,0.0001545676,0.00002935467,0.00005543376,0.00002266525,0.0009423971],"genre_scores_gemma":[0.999616,0.00000517706,0.000012184,0.00005778581,0.00009126837,0.000002301474,0.0001123771,1.822235e-7,0.0001027014],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9407263,"threshold_uncertainty_score":0.276669,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03761865417810292,"score_gpt":0.2074037715267472,"score_spread":0.1697851173486442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}