{"id":"W3167734692","doi":"10.1021/acs.biomac.1c00378","title":"Bio-Orthogonal Nanogels for Multiresponsive Release","year":2021,"lang":"en","type":"article","venue":"Biomacromolecules","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Max-Planck-Gesellschaft; Deutsche Forschungsgemeinschaft","keywords":"Nanogel; Chemistry; Oxidizing agent; Controlled release; Drug delivery; Combinatorial chemistry; Hydrazone; Aqueous solution; Biophysics; Nanotechnology; Materials science; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002700414,0.0002048385,0.0002283122,0.00007672147,0.000205244,0.0001255276,0.0002324213,0.00009313576,0.0003697778],"category_scores_gemma":[0.0005726432,0.0002004138,0.0001681561,0.0002696564,0.0001619319,0.0001402064,0.0001312689,0.00004310961,0.0005861468],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005541763,"about_ca_system_score_gemma":0.0003352523,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001759965,"about_ca_topic_score_gemma":0.0000269326,"domain_scores_codex":[0.9981611,0.0001650241,0.0003250821,0.0005689657,0.0002826989,0.0004971671],"domain_scores_gemma":[0.9986031,0.0003045699,0.0001055716,0.000448621,0.0003479414,0.0001901736],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002187508,0.0001722624,0.0001105065,0.00003158758,0.00001420145,0.000384949,0.00007837523,0.00001123871,0.9937417,0.001473187,0.001722428,0.002040849],"study_design_scores_gemma":[0.0009664854,0.00009045432,0.0004100646,0.00003311384,0.00003312585,0.0000720717,0.00009350258,0.0002501192,0.9908595,0.000495452,0.006421122,0.00027501],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943092,0.0008941835,0.00256137,0.0007108844,0.0005091939,0.000283363,0.0004644207,0.0001584723,0.0001089056],"genre_scores_gemma":[0.9831915,0.00001120564,0.01540202,0.00064358,0.0001261528,0.00009132911,0.00006714057,0.00003857021,0.0004285404],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01284065,"threshold_uncertainty_score":0.8172637,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01547454216972277,"score_gpt":0.2587609600303826,"score_spread":0.2432864178606598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}