{"id":"W3167819168","doi":"10.9778/cmajo.20210069","title":"Assessing the efficacy and safety of hydroxychloroquine as outpatient treatment of COVID-19: a randomized controlled trial","year":2021,"lang":"en","type":"article","venue":"CMAJ Open","topic":"COVID-19 Clinical Research Studies","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women and Children’s Health Research Institute; University of Calgary; University of Alberta","funders":"","keywords":"Hydroxychloroquine; Medicine; Randomized controlled trial; Hazard ratio; Placebo; Confidence interval; Internal medicine; Mechanical ventilation; Coronavirus disease 2019 (COVID-19); Disease; Pathology; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004744256,0.00166516,0.00491199,0.0007448611,0.0007463842,0.001659915,0.001474811,0.003991873,0.008120982],"category_scores_gemma":[0.006398638,0.0007960078,0.003271878,0.0007792187,0.001940974,0.001329991,0.0005879724,0.003210364,0.0007481182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001626029,"about_ca_system_score_gemma":0.002554308,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002854902,"about_ca_topic_score_gemma":0.004118395,"domain_scores_codex":[0.9961999,0.002484288,0.0002937024,0.0004639114,0.0002464598,0.0003117752],"domain_scores_gemma":[0.9957514,0.001725408,0.001142567,0.0002718433,0.0003630558,0.0007457195],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9890698,0.002362783,0.0003133956,0.0009855683,0.001239575,0.0000196082,0.00002134448,0.00008954564,0.0002801419,0.00006397592,0.0003138619,0.005240495],"study_design_scores_gemma":[0.984902,0.01377172,0.0004262494,0.00005982659,0.0004291022,0.000006118407,0.000007662566,0.0001116864,0.00004337522,0.00005384601,0.0001831383,0.000005314173],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9319783,0.02877497,0.001933737,0.002727936,0.003061429,0.02420134,0.002295875,0.0003075221,0.004718862],"genre_scores_gemma":[0.9651967,0.006640652,0.002778736,0.002179941,0.001369629,0.01840981,0.001038461,0.00002662484,0.002359408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008120982,"threshold_uncertainty_score":0.02716738,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0915637000071383,"score_gpt":0.4898313237877479,"score_spread":0.3982676237806095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}