{"id":"W3167936396","doi":"10.1136/sextrans-2021-055009","title":"Efficacy of a carrageenan gel in preventing anal human papillomavirus (HPV) infection: interim analysis of the Lubricant Investigation in Men to Inhibit Transmission of HPV Infection (LIMIT-HPV) randomised controlled trial","year":2021,"lang":"en","type":"article","venue":"Sexually Transmitted Infections","topic":"Seaweed-derived Bioactive Compounds","field":"Agricultural and Biological Sciences","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Centre Hospitalier de l’Université de Montréal; McGill University","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research","keywords":"Medicine; Interim analysis; Transmission (telecommunications); Human papillomavirus; HPV infection; Randomized controlled trial; Interim; Virology; Papillomaviridae; Internal medicine; Gynecology; Cervical cancer; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009094434,0.0002912095,0.001080916,0.0004511114,0.000203984,0.00003406536,0.0001842687,0.000218134,0.0003345418],"category_scores_gemma":[0.000411487,0.0001502148,0.000713227,0.006345164,0.0001823551,0.0002056603,0.00005132218,0.0003657122,4.565809e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001460849,"about_ca_system_score_gemma":0.0001090716,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.008524073,"about_ca_topic_score_gemma":0.01898269,"domain_scores_codex":[0.9960942,0.001178386,0.001501014,0.0005017305,0.0004160527,0.0003085867],"domain_scores_gemma":[0.9980212,0.0007513484,0.0005775099,0.0001842513,0.0003507314,0.0001149976],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01237816,0.001587125,0.09338554,0.00004052729,0.0006800597,0.000001670606,0.001634703,0.002727525,0.8684298,0.00004980808,0.000006294948,0.0190788],"study_design_scores_gemma":[0.07467394,0.0009117569,0.853143,0.00009454515,0.0006001845,0.000002314272,0.0002421041,0.0005904495,0.0693639,0.00009398911,0.00006114601,0.0002226423],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958279,0.00004839283,0.0002857606,0.0002923994,0.0001663646,0.002250761,0.00002758071,0.00004257048,0.001058275],"genre_scores_gemma":[0.9994465,0.00004388377,0.00004380658,0.00004171886,0.00006698306,0.0002140049,0.00008772184,0.000004804827,0.00005065048],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7990659,"threshold_uncertainty_score":0.9989183,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02851751151744427,"score_gpt":0.2783252988242696,"score_spread":0.2498077873068253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}