{"id":"W3168209112","doi":"10.1096/fasebj.24.1_supplement.408.1","title":"Lipid transporters and binding proteins; MsbA and NPC1","year":2010,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"NPC1; Endosome; Flippase; ATP-binding cassette transporter; Biochemistry; Transport protein; Chemistry; Sterol regulatory element-binding protein; Cell biology; Membrane protein; Vesicle; Biology; Sterol; Transporter; Intracellular; Membrane; Cholesterol; Gene; Phospholipid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001839636,0.0004243072,0.0004026763,0.0002697923,0.0004167087,0.000741419,0.0003960718,0.0005538366,0.002992677],"category_scores_gemma":[0.0002368217,0.0001319712,0.00008392766,0.0004406021,0.0004602197,0.0008615325,0.0003994744,0.0005564645,0.001779491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009745506,"about_ca_system_score_gemma":0.0006292039,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001542679,"about_ca_topic_score_gemma":0.001354813,"domain_scores_codex":[0.9999024,0.00001684039,0.000004708908,0.00002489352,0.00003923534,0.00001195021],"domain_scores_gemma":[0.9999067,0.00001446305,0.0000240124,0.000007116286,0.00001701851,0.00003077581],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001178337,0.0001148107,0.002170767,0.001138018,0.00004211671,0.001742089,0.0001912261,0.001637795,0.8846505,0.03930645,0.007853715,0.05997435],"study_design_scores_gemma":[0.00007448452,0.0001918972,0.01202971,0.0001253253,0.00005972537,0.009652243,0.0004066471,0.00728062,0.4797586,0.02139463,0.4689528,0.00007334926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5997444,0.2449617,0.06146871,0.009798815,0.0005573065,0.0001824672,0.004791551,0.001390865,0.07710417],"genre_scores_gemma":[0.8540428,0.05873219,0.02664134,0.0009649089,0.0001987171,0.000138743,0.003983064,0.000123844,0.05517445],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002992677,"threshold_uncertainty_score":0.01001155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01842699681906357,"score_gpt":0.2747053480984242,"score_spread":0.2562783512793607,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}