{"id":"W3168312743","doi":"10.3389/fimmu.2021.678028","title":"Case Report: Combined Intra-Lesional IL-2 and Topical Imiquimod Safely and Effectively Clears Multi-Focal, High Grade Cutaneous Squamous Cell Cancer in a Combined Liver and Kidney Transplant Patient","year":2021,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"Nonmelanoma Skin Cancer Studies","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Medicine; Immunosuppression; Skin cancer; Imiquimod; Population; Context (archaeology); Cancer; Melanoma; Cryotherapy; Organ transplantation; Oncology; Immunology; Dermatology; Internal medicine; Surgery; Cancer research; Transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001691482,0.0006658268,0.003140242,0.0004489822,0.000113706,0.00002270744,0.0001038133,0.0007350626,0.00002542568],"category_scores_gemma":[0.0001892285,0.0005926778,0.0001548919,0.0002663987,0.000738705,0.00004846703,0.0002376826,0.001235902,6.644055e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005687929,"about_ca_system_score_gemma":0.0004782219,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00150052,"about_ca_topic_score_gemma":0.0003632006,"domain_scores_codex":[0.9965986,0.0005627611,0.001010173,0.001066847,0.0001857331,0.000575887],"domain_scores_gemma":[0.99859,0.0004344233,0.0003363457,0.0003688044,0.00005981437,0.000210602],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"case_report","study_design_scores_codex":[0.001687128,0.0009774849,0.01656939,0.01178035,0.001038237,0.4190658,0.002375642,0.000001189119,0.00001937315,0.00004172889,0.001087706,0.545356],"study_design_scores_gemma":[0.04242631,0.011366,0.04407421,0.03450604,0.006228415,0.6189269,0.001324245,0.000487524,0.0001325592,0.0001506785,0.2366031,0.003774003],"study_design_candidate":"case_report","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1380802,0.858409,0.00008067636,0.0001963781,0.001318924,0.001632125,0.0002461489,0.00002357296,0.00001287617],"genre_scores_gemma":[0.0624655,0.934466,0.002230427,0.0001268556,0.00004843681,0.0003866846,0.0001317454,0.00007229578,0.00007202763],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.541582,"threshold_uncertainty_score":0.9996524,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01760181091438958,"score_gpt":0.2698574689219786,"score_spread":0.2522556580075891,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}