{"id":"W3168336339","doi":"10.1101/2021.06.09.447699","title":"Single cell chronoatlas of regenerating mouse livers reveals early Kupffer cell proliferation","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Liver physiology and pathology","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Liver regeneration; Biology; Kupffer cell; Cell biology; Chemokine; Regeneration (biology); Cell; Cell growth; Hepatic stellate cell; Cell type; Liver cytology; Flow cytometry; Immunology; Inflammation; Genetics; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004402057,0.0005178413,0.0009860903,0.0002470447,0.0001359399,0.00006417084,0.0002715244,0.000984289,0.0001104138],"category_scores_gemma":[0.0001459683,0.0005488295,0.0002481397,0.0003072801,0.0001805161,0.0001439028,0.0003590536,0.0009882611,0.00004441659],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002113281,"about_ca_system_score_gemma":0.0007855783,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000605092,"about_ca_topic_score_gemma":0.000002338854,"domain_scores_codex":[0.9970937,0.0003660138,0.0007218544,0.001020489,0.0003085166,0.0004893912],"domain_scores_gemma":[0.9969143,0.00008324112,0.0006670907,0.001261666,0.0008399712,0.0002337212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008361437,0.0005269197,0.02329044,0.001377834,0.000108298,0.00010432,0.0001077619,0.0001269723,0.9739553,0.00006437096,0.0002533637,7.872347e-7],"study_design_scores_gemma":[0.0009333699,0.0003898424,0.05023612,0.0004289564,0.0002988552,6.797301e-8,0.000008897066,0.0001009835,0.9470621,4.605751e-7,0.0001003368,0.000439983],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956759,0.002029063,0.0002889374,0.00007692375,0.0006947864,0.0008904978,0.00009782939,0.0001671724,0.00007889445],"genre_scores_gemma":[0.9901742,0.0001853365,0.008348915,0.000291022,0.0006818355,0.00009707926,0.000004725499,0.0001120853,0.0001047551],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02694568,"threshold_uncertainty_score":0.9996963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01661377877207947,"score_gpt":0.2137730169943571,"score_spread":0.1971592382222776,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}