{"id":"W3168336339","doi":"10.1101/2021.06.09.447699","title":"Single cell chronoatlas of regenerating mouse livers reveals early Kupffer cell proliferation","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Liver physiology and pathology","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Liver regeneration; Biology; Kupffer cell; Cell biology; Chemokine; Regeneration (biology); Cell; Cell growth; Hepatic stellate cell; Cell type; Liver cytology; Flow cytometry; Immunology; Inflammation; Genetics; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003623413,0.0002523962,0.000332065,0.0008899833,0.0002646793,0.0004950009,0.0002399754,0.0002864321,0.003487747],"category_scores_gemma":[0.0001546712,0.0002100242,0.0003372334,0.0005538741,0.0003037931,0.0002369344,0.0003390494,0.0007086472,0.001491672],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003073179,"about_ca_system_score_gemma":0.0001925729,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001069154,"about_ca_topic_score_gemma":0.001559954,"domain_scores_codex":[0.9997763,0.00001261063,0.00001032589,0.00008073179,0.00008261902,0.00003743708],"domain_scores_gemma":[0.9998036,0.00004151046,0.00003698127,0.00004100673,0.00003686475,0.00004011018],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001286601,0.000009677982,0.00154335,0.00006846169,0.00001424242,0.00004202068,0.00005099138,0.0002659553,0.9928911,0.0003112777,0.00044309,0.004231233],"study_design_scores_gemma":[0.00001209534,0.00007622882,0.03211849,0.00001963192,0.00002797303,0.0001792963,0.00008630183,0.004627536,0.9539307,0.000692916,0.008207576,0.00002139945],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8761461,0.004092929,0.07705314,0.000406971,0.0002211842,0.00005160887,0.03183646,0.003375876,0.00681568],"genre_scores_gemma":[0.9090917,0.00253756,0.05114167,0.0004339826,0.00008088928,0.0002241033,0.02223992,0.001273058,0.01297718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003487747,"threshold_uncertainty_score":0.01166767,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01661377877207947,"score_gpt":0.2137730169943571,"score_spread":0.1971592382222776,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}