{"id":"W3168446627","doi":"10.1007/s00285-021-01693-0","title":"Operon dynamics with state dependent transcription and/or translation delays","year":2021,"lang":"en","type":"article","venue":"Journal of Mathematical Biology","topic":"Gene Regulatory Network Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Science Foundation of Sri Lanka; Natural Sciences and Engineering Research Council of Canada; Alexander von Humboldt-Stiftung; National Science Foundation","keywords":"Multistability; Mathematics; Translation (biology); State space; Homoclinic orbit; Operon; Control theory (sociology); Bifurcation; Statistical physics; Computer science; Physics; Gene; Biology; Genetics; Nonlinear system; Messenger RNA; Control (management); Artificial intelligence; Statistics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003716944,0.0001019715,0.0002338633,0.00004433471,0.00002989967,0.00001274146,0.00007024502,0.000120392,0.00004710456],"category_scores_gemma":[0.00003565542,0.0000658737,0.00008040266,0.00007503712,0.0000705164,0.000004808913,0.00001529585,0.00009754005,0.000001683267],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001650649,"about_ca_system_score_gemma":0.00007377697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":5.378279e-7,"about_ca_topic_score_gemma":0.00009105409,"domain_scores_codex":[0.9991656,0.0000965017,0.00035518,0.0001390264,0.00009897079,0.0001447531],"domain_scores_gemma":[0.9994651,0.00003319054,0.0001420796,0.000118152,0.0001567777,0.0000847181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001109876,0.0002609185,0.001818466,0.0001056536,0.0006636078,0.00009666162,0.0001959754,0.0008988195,0.9495389,0.001309982,0.00006136931,0.04393971],"study_design_scores_gemma":[0.01090927,0.01135496,0.004749561,0.0004025277,0.002113411,0.01578001,0.002257155,0.02885306,0.8829708,0.03014004,0.008869502,0.001599758],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7329269,0.0009112266,0.2657369,0.0002410294,0.00002985233,0.00003886142,0.000004126061,0.000001834571,0.0001092537],"genre_scores_gemma":[0.9827778,0.0004059995,0.01647454,0.00007402743,0.00007518769,0.000001133316,0.00002269482,0.00001142059,0.0001571471],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.249851,"threshold_uncertainty_score":0.2686252,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01359076895363201,"score_gpt":0.2503185980138398,"score_spread":0.2367278290602078,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}