{"id":"W3168486292","doi":"10.1101/2021.06.04.447118","title":"A Xeno-free Media for the In Vitro Expansion of Human Spermatogonial Stem Cells","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria; Ottawa Hospital; University of British Columbia","funders":"University of Victoria","keywords":"Fetal bovine serum; Cryopreservation; In vitro; Bovine serum albumin; Stem cell; Biology; Cell biology; Cell culture; Embryonic stem cell; Andrology; Molecular biology; Immunology; Embryo; Biochemistry; Gene; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003754889,0.0004383092,0.0002014866,0.0002813369,0.0001675332,0.0003646029,0.0002200488,0.0001727785,0.001313837],"category_scores_gemma":[0.0001629813,0.00009353677,0.000169509,0.0001905701,0.0002104171,0.0001827232,0.0003244693,0.0003563523,0.0005214499],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001323941,"about_ca_system_score_gemma":0.0002529788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000234608,"about_ca_topic_score_gemma":0.0004688672,"domain_scores_codex":[0.9997906,0.00005459154,0.0000257293,0.00003678283,0.0000759369,0.00001632539],"domain_scores_gemma":[0.9999069,0.00002205942,0.00002054978,0.00001503131,0.00001955777,0.000015909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008858317,0.0000283842,0.0001536276,0.00008066166,0.000005122839,0.00006294254,0.00002570025,0.000076832,0.9963608,0.0001293359,0.00009597014,0.002892027],"study_design_scores_gemma":[0.00001245341,0.0001574449,0.001188564,0.00001595806,0.00001829249,0.0002473835,0.00001330275,0.000300743,0.990154,0.00002972017,0.007857668,0.000004433399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9042403,0.01287796,0.07026631,0.0002628112,0.0003796204,0.0004332685,0.002981492,0.0004492429,0.008108878],"genre_scores_gemma":[0.9169208,0.006461429,0.0568862,0.0001462931,0.0001148109,0.0004259876,0.005945517,0.0002350377,0.01286393],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001313837,"threshold_uncertainty_score":0.004395247,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0211027162049211,"score_gpt":0.2322536088837329,"score_spread":0.2111508926788118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}