{"id":"W3168682353","doi":"10.3390/v13061082","title":"Development of Group B Coxsackievirus as an Oncolytic Virus: Opportunities and Challenges","year":2021,"lang":"en","type":"article","venue":"Viruses","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Vancouver Coastal Health Research Institute; British Columbia Lung Association","keywords":"Oncolytic virus; Virotherapy; Biology; Enterovirus; Virus; Coxsackievirus; Virology; Immunology; Cancer; Cancer research; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000313723,0.0001653979,0.0001986945,0.00006060943,0.00009406149,0.00002704882,0.0001714418,0.0001181496,0.0001260743],"category_scores_gemma":[0.00005621668,0.0001651419,0.00003929891,0.00006101824,0.0001517276,0.00001145305,0.0001728064,0.00006823904,0.00001479866],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001486973,"about_ca_system_score_gemma":0.0004337861,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002090552,"about_ca_topic_score_gemma":0.001279745,"domain_scores_codex":[0.9987711,0.0001417202,0.0002528921,0.0003652071,0.0002268497,0.0002422825],"domain_scores_gemma":[0.9992347,0.00002304648,0.00007002964,0.0003991388,0.0001221868,0.0001509149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005252221,0.0001899107,0.00005947248,0.0000710261,0.0001022222,0.00002238233,0.0003802498,0.000001364817,0.9187757,0.0004859358,0.00006528672,0.07932123],"study_design_scores_gemma":[0.0003908282,0.001083352,0.0003115799,0.00002428094,0.000009734368,0.00001619511,0.001162822,0.00000313962,0.8182368,0.00007029052,0.178518,0.0001730237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9744071,0.0241028,0.00001787484,0.0001353899,0.00004859879,0.0001083355,0.00002503956,0.00001537651,0.001139457],"genre_scores_gemma":[0.9340505,0.06218407,0.001980397,0.001046409,0.0001562837,0.00005072172,0.0001040101,0.00005652148,0.000371063],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1784527,"threshold_uncertainty_score":0.6734291,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1451014821000607,"score_gpt":0.3475720105294262,"score_spread":0.2024705284293655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}