{"id":"W3168714410","doi":"10.1200/jco.2021.39.15_suppl.tps5601","title":"A randomized phase III, two-arm trial of paclitaxel, carboplatin, and maintenance letrozole versus letrozole monotherapy in patients with stage II-IV, primary low-grade serous carcinoma of the ovary or peritoneum.","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"National Institutes of Health","keywords":"Medicine; Letrozole; Carboplatin; Internal medicine; Oncology; Aromatase inhibitor; Clinical endpoint; Serous fluid; Serous carcinoma; Taxane; Surgery; Randomized controlled trial; Chemotherapy; Breast cancer; Aromatase; Cancer; Cisplatin; Ovarian cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002575373,0.002569732,0.00362652,0.0006681201,0.0005436629,0.001496195,0.001581555,0.002569248,0.007545773],"category_scores_gemma":[0.00261728,0.001049415,0.001545561,0.0005521062,0.002124392,0.001651429,0.0006530629,0.004454457,0.001577349],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001112242,"about_ca_system_score_gemma":0.002052644,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00107693,"about_ca_topic_score_gemma":0.002332586,"domain_scores_codex":[0.9991609,0.0004748535,0.0000391586,0.000139569,0.00004841067,0.0001371805],"domain_scores_gemma":[0.9983296,0.0004405939,0.0003306658,0.0001692624,0.00007779788,0.0006521191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9817963,0.01030009,0.0003649705,0.000168424,0.0002036932,0.00002845003,0.00003384684,0.0002443882,0.001763526,0.00005421678,0.0003470172,0.004695037],"study_design_scores_gemma":[0.9307705,0.06785365,0.0005414714,0.000007705358,0.00009107372,0.00001819502,0.00001244187,0.0002561661,0.0001847508,0.00007138641,0.0001854403,0.000007272988],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853623,0.0013791,0.0006742965,0.001067349,0.0007846105,0.007696945,0.001197076,0.0001568244,0.00168153],"genre_scores_gemma":[0.9748923,0.001443334,0.00251809,0.002114913,0.0008051256,0.01144772,0.001831249,0.00003973526,0.004907417],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007545773,"threshold_uncertainty_score":0.0252431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06425841964498205,"score_gpt":0.4032444483881785,"score_spread":0.3389860287431965,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}