{"id":"W3168939335","doi":"10.1039/d1ob00670c","title":"Regio- and diastereoselective Pd-catalyzed aminochlorocyclization of allylic carbamates: scope, derivatization, and mechanism","year":2021,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Chemistry; Allylic rearrangement; Diastereomer; Alkene; Vicinal; Yield (engineering); Derivatization; Catalysis; Regioselectivity; Bond cleavage; Combinatorial chemistry; Stereochemistry; Medicinal chemistry; Organic chemistry; High-performance liquid chromatography","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002572908,0.0005051233,0.0001655088,0.0001547702,0.0001545936,0.0002187882,0.0003806277,0.0002761405,0.0007490245],"category_scores_gemma":[0.0001615492,0.0001468834,0.000167768,0.0001339557,0.0003371371,0.0002755719,0.0002451155,0.0004622646,0.0003045465],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003800823,"about_ca_system_score_gemma":0.00028128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000620506,"about_ca_topic_score_gemma":0.001275144,"domain_scores_codex":[0.9998486,0.00002457165,0.00001349683,0.00003927018,0.00002732636,0.00004674157],"domain_scores_gemma":[0.9999235,0.00001203065,0.00002534686,0.00001437248,0.00001413739,0.00001049006],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008251428,0.00003389461,0.0003096625,0.0001118351,0.000008294548,0.0003010887,0.00007094111,0.0002431269,0.9903717,0.000779106,0.0001107068,0.007577123],"study_design_scores_gemma":[0.000008406149,0.0001331776,0.0004195162,0.000003199603,0.000005952026,0.0003622087,0.00001234089,0.000334276,0.9964885,0.00005142182,0.002175249,0.000005822114],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9476552,0.004421508,0.035,0.0003714443,0.00005427755,0.0001738318,0.0003414453,0.0003486802,0.01163372],"genre_scores_gemma":[0.9892232,0.001501893,0.007409076,0.00007359937,0.00001066018,0.00004061274,0.0001550483,0.00002222145,0.001563699],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007490245,"threshold_uncertainty_score":0.002757728,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008452230899151874,"score_gpt":0.2296088506673793,"score_spread":0.2211566197682275,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}