{"id":"W3169066672","doi":"10.1016/j.cellsig.2021.110066","title":"Cardiac fibrosis: Pathobiology and therapeutic targets","year":2021,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Minnesota Population Center, University of Minnesota; American Heart Association","keywords":"Extracellular matrix; Fibrosis; Cardiac fibrosis; Heart failure; Cardiac function curve; Fibroblast; Medicine; Biology; Bioinformatics; Cancer research; Neuroscience; Cell biology; Pathology; Internal medicine; Cell culture; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002206875,0.0001489469,0.0004040878,0.00004344925,0.0001063144,0.00003040458,0.00003110859,0.0001431236,0.00008223586],"category_scores_gemma":[0.00002141776,0.0001281507,0.0002342785,0.000109526,0.00004824764,0.00002276008,0.00005055725,0.0001909094,0.00001812324],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002259336,"about_ca_system_score_gemma":0.00007670566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004184345,"about_ca_topic_score_gemma":2.720385e-7,"domain_scores_codex":[0.9989622,0.00007838566,0.0002129076,0.0003518595,0.0001293767,0.0002653012],"domain_scores_gemma":[0.9994571,0.00006178844,0.00004017315,0.0002046234,0.000110698,0.0001256335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002246899,0.00002471367,0.002566756,0.00008268331,0.0001159699,0.00004315602,0.0002282365,0.00009911603,0.9916899,0.0001872792,0.00004655059,0.004893137],"study_design_scores_gemma":[0.001124791,0.0001930921,0.004895274,0.0003916423,0.0006505272,0.0001342016,0.0008035969,0.008226641,0.9527472,0.0006861419,0.02965659,0.0004902861],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8475737,0.1426225,0.007650515,0.0002914862,0.0004369724,0.0001769993,0.000007943155,0.00007019863,0.001169657],"genre_scores_gemma":[0.9950531,0.001136618,0.002628729,0.0003097733,0.0003662704,0.00000664172,0.00006912853,0.00003108706,0.0003986876],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1474793,"threshold_uncertainty_score":0.5225832,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01617063268709114,"score_gpt":0.2354794600883848,"score_spread":0.2193088274012936,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}