{"id":"W3169066672","doi":"10.1016/j.cellsig.2021.110066","title":"Cardiac fibrosis: Pathobiology and therapeutic targets","year":2021,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Minnesota Population Center, University of Minnesota; American Heart Association","keywords":"Extracellular matrix; Fibrosis; Cardiac fibrosis; Heart failure; Cardiac function curve; Fibroblast; Medicine; Biology; Bioinformatics; Cancer research; Neuroscience; Cell biology; Pathology; Internal medicine; Cell culture; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007870605,0.0005821738,0.0008697124,0.000584373,0.000427412,0.002289733,0.0004138101,0.001075609,0.003416656],"category_scores_gemma":[0.0005124019,0.0001799221,0.0003435817,0.0004774921,0.001009653,0.001370934,0.0006582324,0.002491484,0.0008871441],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005963848,"about_ca_system_score_gemma":0.000750107,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001702564,"about_ca_topic_score_gemma":0.0004702445,"domain_scores_codex":[0.99975,0.00006051414,0.00001542982,0.00003346769,0.00006489384,0.00007575798],"domain_scores_gemma":[0.9997358,0.00008997659,0.00005930376,0.00001499789,0.00004768578,0.00005219184],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.002243022,0.001441317,0.003932757,0.005260157,0.0001978798,0.00158442,0.0005193332,0.002518415,0.1228606,0.09721055,0.03303262,0.7291989],"study_design_scores_gemma":[0.001187806,0.006017407,0.02138726,0.00534474,0.000503101,0.006433791,0.002076952,0.0058085,0.06975118,0.1288999,0.7523981,0.0001913482],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03324486,0.9125457,0.00514347,0.02703734,0.001520023,0.00007218553,0.000208014,0.0001001655,0.02012817],"genre_scores_gemma":[0.319531,0.6567939,0.004854125,0.004527279,0.003763026,0.0001898764,0.0002699654,0.00003151896,0.01003939],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003416656,"threshold_uncertainty_score":0.01142985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01617063268709114,"score_gpt":0.2354794600883848,"score_spread":0.2193088274012936,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}