{"id":"W3169559325","doi":"10.1530/erc-21-0116","title":"Targeting androgen receptor signaling: a historical perspective","year":2021,"lang":"en","type":"review","venue":"Endocrine Related Cancer","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Terry Fox Research Institute; Prostate Cancer Canada; Prostate Cancer Foundation","keywords":"Prostate cancer; Medicine; Androgen deprivation therapy; Cancer; Disease; Hormonal therapy; Oncology; Prostate; Internal medicine; Androgen; Hormone","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009385725,0.0008203447,0.001056032,0.002972399,0.0004962326,0.001614599,0.000907436,0.001738424,0.002676812],"category_scores_gemma":[0.0017203,0.0003573362,0.0005551975,0.002747096,0.00111178,0.002905112,0.0008355245,0.004099818,0.001766165],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001145934,"about_ca_system_score_gemma":0.001496061,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002024425,"about_ca_topic_score_gemma":0.003334787,"domain_scores_codex":[0.9996898,0.00007649828,0.00003969072,0.00005902271,0.00009842171,0.00003650696],"domain_scores_gemma":[0.9992132,0.0004613287,0.00005767613,0.00002077773,0.0001918848,0.00005506167],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001623159,0.0001136733,0.0003518396,0.02370993,0.00009030191,0.0009530641,0.0004292624,0.0004686169,0.001540294,0.02889225,0.1435048,0.7997836],"study_design_scores_gemma":[0.000006814222,0.00005019351,0.0003436479,0.004275005,0.00003316933,0.001502379,0.00008696281,0.00003112332,0.0001200399,0.002925089,0.9906116,0.00001402563],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005733794,0.9974686,0.00004193249,0.0007482754,0.000681773,0.000001213024,0.000007026588,0.000002668516,0.0009912864],"genre_scores_gemma":[0.0006684216,0.9971101,0.00004691606,0.00106913,0.0007535382,0.000002577024,0.000009605756,0.00000132304,0.0003383178],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002972399,"threshold_uncertainty_score":0.008954823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05901755478858615,"score_gpt":0.3948831400957289,"score_spread":0.3358655853071427,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}