{"id":"W3169652198","doi":"10.1093/mutage/geab021","title":"Comparative potency analysis of whole smoke solutions in the bacterial reverse mutation test","year":2021,"lang":"en","type":"article","venue":"Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"U.S. Food and Drug Administration; National Institutes of Health; National Center for Toxicological Research","keywords":"Ames test; Potency; Genotoxicity; Chemistry; Smoke; Toxicology; Food science; Tobacco smoke; Pharmacology; Toxicity; Salmonella; Biochemistry; In vitro; Biology; Genetics; Bacteria; Organic chemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001589171,0.0009616118,0.0006844971,0.001351401,0.0002694483,0.0005287058,0.0006414952,0.0007146319,0.001318443],"category_scores_gemma":[0.001886791,0.0002917804,0.0008492703,0.001100714,0.0003551453,0.0003938381,0.000684821,0.0006483124,0.0004772766],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002942965,"about_ca_system_score_gemma":0.0003931811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000983165,"about_ca_topic_score_gemma":0.001629558,"domain_scores_codex":[0.9971077,0.0007680652,0.0002449272,0.0003776113,0.00136799,0.0001336138],"domain_scores_gemma":[0.9983877,0.0004789884,0.0002651246,0.0001797545,0.0006068977,0.00008156617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001704663,0.00009905609,0.001765644,0.00009615249,0.00002760788,0.00002613039,0.00006499598,0.0003970687,0.9919602,0.00008246813,0.00003330073,0.005276773],"study_design_scores_gemma":[0.00000773283,0.002033401,0.007312553,0.0000109276,0.0000599486,0.00009509107,0.00007610326,0.001456421,0.9881499,0.00008211603,0.0006981684,0.00001757941],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9148482,0.002537588,0.07638178,0.0001217958,0.00009293186,0.0006391125,0.001310474,0.0002992791,0.003768961],"genre_scores_gemma":[0.922345,0.002865438,0.06525546,0.0001534887,0.00003841523,0.0006919883,0.002627689,0.00009812394,0.005924455],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001589171,"threshold_uncertainty_score":0.008404374,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03432420784746972,"score_gpt":0.2980405580601446,"score_spread":0.2637163502126749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}