{"id":"W3169652452","doi":"10.1200/jco.2021.39.15_suppl.4552","title":"The impact of antibiotic (Ab) exposure on clinical outcomes in patients with metastatic renal cell carcinoma (mRCC) treated with immune checkpoint inhibitors (ICI) or VEGF targeted therapy (VEGF-TT).","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"William Osler Health System; University of Calgary","funders":"","keywords":"Medicine; Internal medicine; Renal cell carcinoma; Oncology; Proportional hazards model; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006045619,0.00010423,0.0002385606,0.0004225567,0.0002460815,0.0004866252,0.0002336272,0.000238266,0.001108964],"category_scores_gemma":[0.002287088,0.0001076419,0.0003430128,0.0007074262,0.0002082112,0.0003097198,0.0003641932,0.0004347378,0.0001257875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005662328,"about_ca_system_score_gemma":0.0004365582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003652655,"about_ca_topic_score_gemma":0.005896111,"domain_scores_codex":[0.9993973,0.0001559992,0.00007455075,0.0001512823,0.0001106185,0.0001103368],"domain_scores_gemma":[0.9971734,0.0005335603,0.001693705,0.00007722787,0.0001701633,0.0003519126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000131032,0.00001429171,0.9985746,0.000007333379,0.0000287155,0.00002901404,0.00001152823,0.00003673151,0.00008499908,0.000006344272,0.00007826435,0.000997154],"study_design_scores_gemma":[0.000006328326,0.0001040785,0.9992825,0.000004780225,0.0000262665,0.0001532279,0.00004871939,0.0001913014,0.00005114876,0.00001033207,0.000119663,0.000001616162],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986445,0.0004557104,0.00005347408,0.00007403693,0.00000494681,0.000005852695,0.0004383695,0.000002254851,0.0003208472],"genre_scores_gemma":[0.9995746,0.00006987957,0.00003091989,0.00002129447,0.000007781736,0.000003236456,0.0002593446,6.607885e-7,0.00003228111],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003652655,"threshold_uncertainty_score":0.007262826,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06997620596433854,"score_gpt":0.406455992538337,"score_spread":0.3364797865739985,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}