{"id":"W3169673451","doi":"10.1016/j.jim.2021.113083","title":"Immunocartography: Charting vaccine-driven immunity by applying single cell proteomics to an in vitro human model","year":2021,"lang":"en","type":"article","venue":"Journal of Immunological Methods","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Fluidigm (Canada); York University; Sanofi (Canada)","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Adjuvant; Immune system; Mass cytometry; Acquired immune system; Immunology; Antigen; Computational biology; Biology; Immunity; Computer science; Phenotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005417278,0.0005319192,0.0004364275,0.000411009,0.0002659089,0.0007121924,0.000447954,0.0006889832,0.001498946],"category_scores_gemma":[0.0002808178,0.0002325402,0.000360961,0.0002589898,0.0005398325,0.0004553363,0.0002583631,0.0009862037,0.000776256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003796103,"about_ca_system_score_gemma":0.0003940843,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001166313,"about_ca_topic_score_gemma":0.001517165,"domain_scores_codex":[0.9997638,0.0000652517,0.00001104481,0.00007462462,0.00004661186,0.00003861754],"domain_scores_gemma":[0.9997817,0.00008033415,0.00002742117,0.00005178889,0.00003306117,0.00002581423],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001568942,0.00003953524,0.0002226705,0.00006519596,0.000005949556,0.00007005729,0.0000363442,0.0003137083,0.9950913,0.000397202,0.000156634,0.003444396],"study_design_scores_gemma":[0.000008374414,0.0002742833,0.0009655941,0.000006597314,0.00001820623,0.0002330344,0.00003872903,0.004543446,0.9911618,0.0002770011,0.002466019,0.000006834699],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.640972,0.007773947,0.3385919,0.0008588664,0.000443568,0.0003241294,0.002055504,0.001373283,0.00760685],"genre_scores_gemma":[0.9084445,0.003445172,0.08185876,0.0003074652,0.00006417136,0.0001645503,0.0009335476,0.0001935135,0.004588402],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001498946,"threshold_uncertainty_score":0.00501442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04401303270369274,"score_gpt":0.3268000385643035,"score_spread":0.2827870058606108,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}