{"id":"W3170059573","doi":"10.21203/rs.3.rs-496481/v1","title":"Pcyt2 Deficiency Causes Age-Dependant Development of Non-Alcoholic Steatohepatitis and Insulin Resistance that Could be Attenuated with Phospho-Ethanolamine","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of Guelph","funders":"Canadian Institutes of Health Research","keywords":"Insulin resistance; Steatohepatitis; Endocrinology; Internal medicine; Fatty liver; Carbohydrate metabolism; Metabolic syndrome; Steatosis; Insulin; Metabolism; Biology; Lipid metabolism; Chemistry; Medicine; Diabetes mellitus; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001921181,0.0004311865,0.0003257866,0.0005343184,0.0001634734,0.0003087095,0.0002224906,0.0005376132,0.003675468],"category_scores_gemma":[0.0001407704,0.0002165986,0.0003049847,0.000213879,0.0003551981,0.0003144757,0.0003440806,0.0006875457,0.001020845],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00021206,"about_ca_system_score_gemma":0.0001603402,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003744246,"about_ca_topic_score_gemma":0.0005744066,"domain_scores_codex":[0.9998197,0.00002428945,0.0000164494,0.00004947432,0.00005739449,0.00003268967],"domain_scores_gemma":[0.9998108,0.00001844328,0.00006959211,0.0000197864,0.00001724927,0.00006410612],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005916937,0.00005722809,0.0004970963,0.00004434944,0.00001143999,0.0002550579,0.00001986191,0.00005416087,0.9960874,0.0002228115,0.0002060625,0.001952798],"study_design_scores_gemma":[0.00006783472,0.0004390066,0.009524569,0.00001976085,0.00002830529,0.001175318,0.00005691489,0.0009468653,0.9792472,0.0002194946,0.008264044,0.00001074146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800857,0.002136519,0.01027784,0.0005319419,0.0001904584,0.00004550268,0.002616961,0.000463444,0.003651635],"genre_scores_gemma":[0.956648,0.001744574,0.008257554,0.0001844478,0.00006041114,0.0001182718,0.002784968,0.0002598705,0.02994192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003675468,"threshold_uncertainty_score":0.01229566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07856707966183157,"score_gpt":0.3654736491846275,"score_spread":0.286906569522796,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}