{"id":"W3170169033","doi":"10.1096/fasebj.2021.35.s1.02423","title":"Genetic deletion of soluble epoxide hydrolase preserves cardiac function and limits inflammation in acute lipopolysaccharide injury","year":2021,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Epoxide hydrolase 2; Gene knockdown; Lipopolysaccharide; Inflammation; Pharmacology; Inflammasome; Chemistry; Medicine; Immunology; Biochemistry; Enzyme; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002791367,0.0004879266,0.0004341259,0.0003642078,0.0002468134,0.0003817333,0.0003379205,0.0004931051,0.003044182],"category_scores_gemma":[0.0001269751,0.0002564308,0.0004377225,0.0001940671,0.0004886968,0.000395361,0.0003072552,0.0009038346,0.0007822534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002138276,"about_ca_system_score_gemma":0.0002832326,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000349653,"about_ca_topic_score_gemma":0.0006455905,"domain_scores_codex":[0.9997252,0.00002806515,0.00004533039,0.00006445422,0.00006349295,0.00007347303],"domain_scores_gemma":[0.9997168,0.0000218316,0.0001044664,0.00002754081,0.00002528331,0.0001040087],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003466627,0.00007877911,0.000163617,0.0000600519,0.00000822248,0.00006654757,0.00001894776,0.00004959423,0.9979825,0.0001185839,0.00006594876,0.001040535],"study_design_scores_gemma":[0.0001430629,0.001748657,0.005064663,0.00003223691,0.00004658194,0.0004490591,0.00010009,0.0007500614,0.9867957,0.00009542629,0.004762706,0.00001183067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853436,0.001823267,0.007856372,0.0003013161,0.00015993,0.0001595437,0.001969254,0.0003184853,0.002068269],"genre_scores_gemma":[0.9768369,0.002062035,0.006385251,0.0001352147,0.00004825897,0.0003231877,0.00182647,0.00008694,0.01229587],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003044182,"threshold_uncertainty_score":0.01018381,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01002318184166612,"score_gpt":0.244126249705227,"score_spread":0.2341030678635609,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}