{"id":"W3170205587","doi":"10.3389/fmicb.2021.647410","title":"Autophagy Receptor Protein Tax1-Binding Protein 1/TRAF6-Binding Protein Is a Cellular Substrate of Enteroviral Proteinase","year":2021,"lang":"en","type":"article","venue":"Frontiers in Microbiology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Autophagy; Optineurin; Cell biology; Mitophagy; Biology; Ubiquitin; Viral replication; Signal transducing adaptor protein; ATG16L1; Protein degradation; Biochemistry; Signal transduction; Virology; Virus; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009749314,0.0004457792,0.0002364573,0.0002717172,0.0003090565,0.0003881614,0.0001136958,0.0002710016,0.00127419],"category_scores_gemma":[0.000100545,0.0001121334,0.0003722832,0.0002235894,0.0001407601,0.0001906771,0.0001895512,0.0003935669,0.0006479884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004457193,"about_ca_system_score_gemma":0.0002156622,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005752449,"about_ca_topic_score_gemma":0.0006676112,"domain_scores_codex":[0.9998646,0.00001543138,0.00001137147,0.00003355635,0.00004160958,0.00003354144],"domain_scores_gemma":[0.9999199,0.000006287783,0.00003393128,0.000008161585,0.00001294732,0.00001869123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009853421,0.000009858115,0.0005125898,0.000049631,0.000005747671,0.0000739327,0.000006655485,0.00006541091,0.9979741,0.00008804435,0.00004030733,0.001075326],"study_design_scores_gemma":[0.000012458,0.0001378574,0.01537147,0.00001247943,0.00001887,0.002058104,0.00004082931,0.001339207,0.975173,0.0001391776,0.005687601,0.000009034115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859913,0.006314298,0.004174268,0.0001177653,0.00003086086,0.00002518427,0.001139175,0.0001158959,0.002091125],"genre_scores_gemma":[0.9920744,0.001718122,0.002280606,0.00002801967,0.000008798779,0.000016925,0.001614645,0.00001502621,0.002243468],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00127419,"threshold_uncertainty_score":0.004262626,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009759763803223647,"score_gpt":0.2329271776692154,"score_spread":0.2231674138659918,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}