{"id":"W3170298560","doi":"10.21203/rs.3.rs-560501/v1","title":"Bacillus Licheniformis PF9 Improves Barrier Function and Alleviates Inflammatory Responses Against Enterotoxigenic Escherichia Coli F4 Infection in the Porcine Intestinal Epithelial Cells","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Agriculture and Agri-Food Canada","funders":"China Scholarship Council; Agriculture and Agri-Food Canada; Swine Innovation Porc; University of Manitoba","keywords":"Bacillus licheniformis; Enterotoxigenic Escherichia coli; Microbiology; Escherichia coli; Barrier function; Tight junction; Function (biology); Biology; Chemistry; Enterotoxin; Bacteria; Bacillus subtilis; Cell biology; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001775522,0.0005894368,0.0005167749,0.0003184905,0.0001697527,0.0002457368,0.0001870265,0.0003813799,0.001382388],"category_scores_gemma":[0.000145965,0.0001099337,0.0002865009,0.0001805568,0.0002183201,0.0002453737,0.0002201966,0.0006009773,0.0003057588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001818885,"about_ca_system_score_gemma":0.0002070979,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006168331,"about_ca_topic_score_gemma":0.0007546562,"domain_scores_codex":[0.9997906,0.00004340662,0.00002102974,0.00002862661,0.00005877352,0.00005758916],"domain_scores_gemma":[0.9998837,0.0000134511,0.00003793953,0.00001344497,0.00001585758,0.00003565133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003694619,0.0001987905,0.000218428,0.0001327156,0.00000751941,0.00007448263,0.0000183692,0.00004899676,0.9968325,0.00001343116,0.00004957328,0.002035755],"study_design_scores_gemma":[0.00007644101,0.00532441,0.01249909,0.00003981001,0.00003341232,0.0004876643,0.0001222016,0.0006058911,0.9775521,0.00003418191,0.003214517,0.00001019492],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945019,0.002951793,0.0009431971,0.0001207946,0.00004720075,0.00003422877,0.0002027499,0.0000866312,0.001111492],"genre_scores_gemma":[0.9956363,0.00103107,0.001118069,0.0000672666,0.0000148822,0.00003322782,0.0003585574,0.00001039082,0.001730392],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001382388,"threshold_uncertainty_score":0.004624546,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02320398085099055,"score_gpt":0.3179211936748305,"score_spread":0.2947172128238399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}