{"id":"W3170304991","doi":"10.21203/rs.3.rs-566597/v1","title":"Early changes in quantitative ultrasound imaging parameters during neoadjuvant chemotherapy to predict recurrence in patients with locally advanced breast cancer","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"Terry Fox Foundation","keywords":"Breast cancer; Medicine; Chemotherapy; Ultrasound; Cancer; Ultrasound imaging; Radiology; Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048519,0.0002115025,0.0002438138,0.000434156,0.00008875617,0.0003111443,0.0001450051,0.0002313992,0.0005217392],"category_scores_gemma":[0.002058743,0.00009890796,0.000170277,0.0002501729,0.0001496462,0.0002140822,0.0001387309,0.0001888034,0.000147027],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002014151,"about_ca_system_score_gemma":0.0001128335,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004914477,"about_ca_topic_score_gemma":0.0006116296,"domain_scores_codex":[0.9998122,0.00006437793,0.00002335297,0.00003084921,0.00004714421,0.00002211228],"domain_scores_gemma":[0.9989836,0.000382615,0.0003738516,0.00005611511,0.0001272575,0.00007650944],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001867461,0.00009083013,0.9639973,0.00004606134,0.00004183235,0.0001311375,0.0000858268,0.0007512211,0.0113858,0.0000125546,0.0001058215,0.02148413],"study_design_scores_gemma":[0.00001708133,0.000988223,0.9907081,0.000008646445,0.00004951653,0.0007143161,0.0001215384,0.00334036,0.003750154,0.00002882712,0.0002629767,0.00001019898],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990126,0.0002870352,0.0004444077,0.00001626354,0.000003181686,0.000007268985,0.00005639653,0.000009893864,0.0001629342],"genre_scores_gemma":[0.9995193,0.00004336956,0.0002902973,0.000004701451,0.000003979938,0.000006559468,0.00006949643,0.000001366759,0.00006091071],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005217392,"threshold_uncertainty_score":0.00256598,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01609674247483277,"score_gpt":0.333506625080529,"score_spread":0.3174098826056962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}