{"id":"W3170482429","doi":"10.1101/2021.06.08.447607","title":"The cell adhesion molecule Sdk1 shapes assembly of a retinal circuit that detects localized edges","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Consejo Nacional de Ciencia y Tecnología","keywords":"Neuroscience; Biology; Retinal ganglion cell; Cell type; Dendrite (mathematics); Feature (linguistics); Retinal; Calcium imaging; Retina; Cell; Chemistry; Genetics; Calcium; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005874606,0.0005176978,0.0004594103,0.00008841084,0.0002167577,0.0002017658,0.0007504714,0.0006255935,0.00001849246],"category_scores_gemma":[0.0002718754,0.0004597167,0.0002938353,0.0002359623,0.0001943066,0.000008517856,0.0007794588,0.0004019609,0.000009636415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004814216,"about_ca_system_score_gemma":0.0007133023,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002453653,"about_ca_topic_score_gemma":0.000008251677,"domain_scores_codex":[0.997314,0.0002739812,0.0004946915,0.0009349941,0.0004541452,0.0005281562],"domain_scores_gemma":[0.9978409,0.00005225772,0.0004979846,0.0009424703,0.0004929694,0.0001733906],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001026386,0.00008974856,0.001927757,0.0003145603,0.0001132672,0.00002165135,0.00001979784,0.000009386256,0.9969385,0.00003604432,0.0004179697,0.000008632778],"study_design_scores_gemma":[0.0005040861,0.0001059648,0.01035901,0.0002329103,0.00007905481,3.752324e-8,0.00005787061,0.00003825786,0.9842287,0.00000228393,0.003835085,0.0005567761],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875148,0.008810736,0.002493717,0.00009452912,0.0004307131,0.0004599468,0.00002806413,0.00004998306,0.00011749],"genre_scores_gemma":[0.9957009,0.002812088,0.0009876851,0.0001110221,0.0001467494,0.0001115442,0.00000275894,0.00009510871,0.00003212721],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01270988,"threshold_uncertainty_score":0.9997855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01317785177642208,"score_gpt":0.2118208123703385,"score_spread":0.1986429605939164,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}