{"id":"W3170645484","doi":"10.1096/fasebj.2021.35.s1.03200","title":"Sarcoplasmic Reticulum Ca 2+ Handling in Gastrocnemius Muscles from 10‐week‐old C57 and D2‐ mdx Mice","year":2021,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"","keywords":"Duchenne muscular dystrophy; mdx mouse; Dystrophin; Internal medicine; Endocrinology; Endoplasmic reticulum; Creatine kinase; Ryanodine receptor; SERCA; Muscular dystrophy; Medicine; Muscle weakness; Sarcoplasm; Chemistry; Pathology; ATPase; Calcium; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004394354,0.00107148,0.0004924585,0.001983036,0.0006515224,0.0006356751,0.0006996868,0.001250018,0.005186885],"category_scores_gemma":[0.0002111841,0.0007140253,0.0008031046,0.0005488147,0.00103161,0.0007812183,0.0005194343,0.002052511,0.001441251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007954642,"about_ca_system_score_gemma":0.0004387922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002644426,"about_ca_topic_score_gemma":0.004339657,"domain_scores_codex":[0.9994926,0.0000344309,0.0001005134,0.0001674521,0.00008727318,0.0001176792],"domain_scores_gemma":[0.9990315,0.00009398985,0.0002702666,0.00007679061,0.00009916568,0.0004283114],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001279609,0.0002192007,0.001101933,0.0000613708,0.00001958217,0.0001707765,0.000125639,0.00006188248,0.995577,0.00008662351,0.0002236378,0.001072679],"study_design_scores_gemma":[0.0004215657,0.003453876,0.1178703,0.0001014976,0.0001551624,0.001576591,0.0006580896,0.00135998,0.8663652,0.0002324788,0.007721198,0.00008409487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9807426,0.001143512,0.002981185,0.0004096327,0.0001139258,0.0002405794,0.01012547,0.0002550895,0.003988146],"genre_scores_gemma":[0.9303421,0.002151534,0.009878023,0.0009596348,0.00007705747,0.001340764,0.01674495,0.0005206062,0.03798527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005186885,"threshold_uncertainty_score":0.01735187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007927768764694192,"score_gpt":0.2132220000378273,"score_spread":0.2052942312731331,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}