{"id":"W3170651335","doi":"10.1093/ndt/gfab078.008","title":"MO072APABETALONE DOWNREGULATES FIBROTIC, INFLAMMATORY AND CALCIFIC PROCESSES IN RENAL MESANGIAL CELLS WHICH MAY CONTRIBUTE TO REDUCED CARDIAC EVENTS OBSERVED IN CKD PATIENTS","year":2021,"lang":"en","type":"article","venue":"Nephrology Dialysis Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Resverlogix (Canada)","funders":"","keywords":"Medicine; Fibrosis; Inflammation; Kidney; Kidney disease; Osteopontin; Myofibroblast; Gene expression; Nephrology; Endocrinology; Cancer research; Internal medicine; Pathology; Biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001268391,0.0002024873,0.0003269519,0.0001742037,0.00009656798,0.0002442046,0.0001424365,0.0001556874,0.002858145],"category_scores_gemma":[0.0001071245,0.0001017844,0.000236861,0.0001000634,0.0001449945,0.0001470263,0.0001037167,0.0005198487,0.0004135991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009353204,"about_ca_system_score_gemma":0.0002124567,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003624455,"about_ca_topic_score_gemma":0.0007849078,"domain_scores_codex":[0.999935,0.00001130729,0.000004887999,0.00001249073,0.00001754297,0.00001871058],"domain_scores_gemma":[0.9999465,0.000005675789,0.00001302941,0.000003832831,0.000009430611,0.00002160412],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002921263,0.0003076894,0.001656031,0.000271671,0.00006787228,0.00004284952,0.00001779231,0.00006802962,0.9768541,0.0000609309,0.0003783414,0.01735332],"study_design_scores_gemma":[0.00183158,0.01719124,0.1242688,0.00009013466,0.0004356236,0.0007478875,0.0001826527,0.001506622,0.8313088,0.000279121,0.02212541,0.00003211038],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869747,0.008916482,0.001195878,0.0002710531,0.0001130327,0.00005348339,0.0006372153,0.0001560305,0.001682171],"genre_scores_gemma":[0.9911868,0.003171186,0.0009503353,0.0001517636,0.00004052202,0.00007888378,0.0004930022,0.00001654507,0.003911094],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002858145,"threshold_uncertainty_score":0.009561419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01174059988176801,"score_gpt":0.2499091192391824,"score_spread":0.2381685193574144,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}