{"id":"W3170667431","doi":"10.1111/jcmm.16681","title":"Pro‐inflammatory signals induce 20α‐HSD expression in myometrial cells: A key mechanism for local progesterone withdrawal","year":2021,"lang":"en","type":"article","venue":"Journal of Cellular and Molecular Medicine","topic":"Pregnancy-related medical research","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Canadian Institutes of Health Research; March of Dimes Foundation","keywords":"Myometrium; Inflammation; Lipopolysaccharide; Endocrinology; Internal medicine; Transcription (linguistics); NFKB1; Transcription factor; Proinflammatory cytokine; NF-κB; Biology; Gene expression; Chemistry; Molecular biology; Uterus; Gene; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002016948,0.0002728869,0.0009484894,0.0006011634,0.00005505823,0.0000188921,0.0001754386,0.0004837425,0.0001131886],"category_scores_gemma":[0.002550378,0.0001978293,0.0001810704,0.0005115267,0.0002510071,0.000122358,0.0001050677,0.001406319,0.000002768822],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001405046,"about_ca_system_score_gemma":0.001005375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005277826,"about_ca_topic_score_gemma":0.000002358051,"domain_scores_codex":[0.9962421,0.0002655122,0.001081492,0.0003677585,0.001516945,0.0005262126],"domain_scores_gemma":[0.9974362,0.0002523245,0.0003694519,0.0003005021,0.0008488059,0.0007927257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001193247,0.0003157003,0.00004120994,0.000560048,0.0001357781,0.007237162,0.0005079343,0.000007989986,0.9790207,0.0003006156,0.0004307489,0.01024885],"study_design_scores_gemma":[0.01678484,0.00287519,0.00005697021,0.0112689,0.0002943405,0.0006443288,0.0006306369,0.0005660781,0.9633849,0.001319155,0.00198934,0.0001852792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6152998,0.05671268,0.3181184,0.00665042,0.0008567853,0.001812848,0.000004550739,0.00002614483,0.0005184425],"genre_scores_gemma":[0.9918541,0.002375918,0.003758835,0.0009469822,0.0005943822,0.00003918096,0.0000178989,0.00006425988,0.000348433],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3765543,"threshold_uncertainty_score":0.8067243,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02074954102937133,"score_gpt":0.2982838762463103,"score_spread":0.277534335216939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}