{"id":"W3170808027","doi":"10.1096/fasebj.2021.35.s1.01820","title":"Commensal Bacteria Derived Metabolite Butyrate Restores the Epithelial Mitochondrial Network Disrupted by the Crohn's Disease‐Associated Pathobiont Adherent Invasive <i>E‐coli</i> Infection","year":2021,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Biology; Mitochondrion; Butyrate; Flow cytometry; Cell biology; Microbiology; Molecular biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001293584,0.0003207224,0.0004151282,0.0001590932,0.0001481232,0.0003377953,0.000158139,0.000304862,0.001095178],"category_scores_gemma":[0.0001149569,0.0001104573,0.0002862151,0.0001229161,0.000180187,0.0002233124,0.0002213028,0.0006676179,0.0003213942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002076224,"about_ca_system_score_gemma":0.0002258197,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007330956,"about_ca_topic_score_gemma":0.001003922,"domain_scores_codex":[0.9998275,0.0000287861,0.00002352639,0.00002580793,0.00004039513,0.00005394384],"domain_scores_gemma":[0.9998765,0.00001151528,0.00003632481,0.00001736554,0.00002175753,0.00003640037],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002174708,0.00003841254,0.000152085,0.00004259998,0.000003387682,0.00002655033,0.000009343705,0.00002425025,0.9987068,0.00001469209,0.0000290928,0.0007353008],"study_design_scores_gemma":[0.00002705771,0.00112431,0.00932217,0.00002223023,0.00002092517,0.0002228437,0.0001095046,0.0005258353,0.986447,0.00003256687,0.002140609,0.000005003025],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956843,0.001335905,0.001424944,0.0001801304,0.00004748175,0.00003031407,0.0004344917,0.00007508739,0.0007873381],"genre_scores_gemma":[0.9948345,0.0008854035,0.001764636,0.0001202836,0.00001012635,0.00003981685,0.0007050508,0.00002015993,0.001620015],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001095178,"threshold_uncertainty_score":0.003663719,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01175077711520488,"score_gpt":0.24334617415879,"score_spread":0.2315953970435851,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}