{"id":"W3170984382","doi":"10.30683/1927-7229.2020.09.01","title":"Lentinan, a Shiitake Mushroom ß-Glucan, Downregulates the Enhanced PD-L1 Expression Induced by Platinum Compounds in Gastric Cancer Cells -","year":2020,"lang":"en","type":"article","venue":"Journal of Analytical Oncology","topic":"Fungal Biology and Applications","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Lentinan; Cancer; Cancer cell; Cancer research; Immune system; Immunotherapy; Medicine; Immune checkpoint; Chemotherapy; Cisplatin; Pharmacology; Immunology; Chemistry; Internal medicine; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003135911,0.0001458787,0.0005779066,0.00009101341,0.00007414553,0.00001049203,0.0002186718,0.0002488808,0.0003624584],"category_scores_gemma":[0.0001998828,0.0000876241,0.0001538835,0.0004483039,0.0001735799,0.00005883685,0.00005689408,0.0008980147,0.00002301383],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001628297,"about_ca_system_score_gemma":0.0003206235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002113962,"about_ca_topic_score_gemma":0.0000262731,"domain_scores_codex":[0.998499,0.000145843,0.0006848315,0.000198431,0.0001943657,0.0002775499],"domain_scores_gemma":[0.9986038,0.0004974504,0.0003730943,0.0001341511,0.0001466153,0.0002448391],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009372186,0.0003562187,0.002474257,0.00001720638,0.0000868624,0.00004517865,0.0003309176,0.00005003223,0.9583421,0.00008446915,0.03530201,0.001973468],"study_design_scores_gemma":[0.01551263,0.01234645,0.1711098,0.0006087353,0.001316845,0.0005213813,0.00261059,0.00518099,0.5959216,0.0007246201,0.1934398,0.0007065809],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.945538,0.0003545533,0.0002213618,0.05189157,0.0001308942,0.000193226,0.000009894417,0.000009012324,0.001651472],"genre_scores_gemma":[0.9950125,0.0001609204,0.000365867,0.003902778,0.0003646484,0.00001092109,0.000006651441,0.00001015807,0.0001655069],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3624205,"threshold_uncertainty_score":0.3968666,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03396649312828448,"score_gpt":0.3318840122357954,"score_spread":0.297917519107511,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}