{"id":"W3171418615","doi":"10.1096/fasebj.27.1_supplement.646.12","title":"Modulating Myeloperoxidase‐Induced Endothelial Permeability by a Carbon Monoxide‐Releasing Molecule, CORM‐3","year":2013,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Lawson Health Research Institute","funders":"","keywords":"Myeloperoxidase; Chemistry; Hypochlorous acid; Inflammation; Reactive oxygen species; Biochemistry; Oxidative stress; Endothelial dysfunction; Neutrophil extracellular traps; Pharmacology; Immunology; Biology; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003268553,0.0004298904,0.000197283,0.0001625516,0.0001338792,0.0002182606,0.0003619618,0.0003885107,0.001849155],"category_scores_gemma":[0.0002479985,0.00007520983,0.0002398567,0.0001264945,0.0003535886,0.000165955,0.0001800081,0.0006037318,0.0003374114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003678064,"about_ca_system_score_gemma":0.0003467285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008044419,"about_ca_topic_score_gemma":0.0006830976,"domain_scores_codex":[0.9998409,0.00004283492,0.0000121289,0.00002061563,0.00004007627,0.00004349848],"domain_scores_gemma":[0.9998285,0.00003459581,0.00005838507,0.00002115215,0.00002477946,0.00003256385],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004465301,0.0001163788,0.0001211374,0.00009426117,0.000007607626,0.00008452765,0.00001324248,0.00006477049,0.9960012,0.0001657465,0.000161087,0.002723487],"study_design_scores_gemma":[0.0001189683,0.000786782,0.002397989,0.000008780335,0.00001663998,0.000225267,0.00001539776,0.0007453475,0.9924468,0.0000569215,0.003177098,0.000003915859],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856862,0.004144376,0.004991475,0.0008821551,0.00017292,0.0001401461,0.0004292371,0.0001763252,0.003377041],"genre_scores_gemma":[0.9916309,0.001208366,0.004057795,0.0002037399,0.00004266415,0.00007357502,0.0003262141,0.00001539195,0.002441401],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001849155,"threshold_uncertainty_score":0.006186008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01023965293050412,"score_gpt":0.2239357714080188,"score_spread":0.2136961184775147,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}