{"id":"W3171550259","doi":"10.1101/2021.06.14.448190","title":"Preterm birth is associated with xenobiotics and predicted by the vaginal metabolome","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Preterm Birth and Chorioamnionitis","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institute for Advanced Research","funders":"Canadian Institute for Advanced Research; National Institute of Nursing Research; University of Pennsylvania","keywords":"Metabolome; Microbiome; Gestation; Metabolite; Medicine; Metabolomics; Obstetrics; Physiology; Pregnancy; Biology; Bioinformatics; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004159237,0.0007030336,0.0009585249,0.0001521239,0.0002480635,0.0003797872,0.0003853324,0.0005776508,0.0001172989],"category_scores_gemma":[0.0003237915,0.0005300306,0.0001509869,0.000558952,0.000383641,0.0001431969,0.0004266906,0.001470956,0.000004477462],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001911296,"about_ca_system_score_gemma":0.0009321171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004263239,"about_ca_topic_score_gemma":0.000004146852,"domain_scores_codex":[0.9967858,0.0002063677,0.0005134284,0.001086232,0.0007032715,0.0007049168],"domain_scores_gemma":[0.9967992,0.0001098546,0.0004501431,0.001386369,0.0007534623,0.0005009971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008862271,0.001187203,0.4991794,0.003090407,0.008527231,0.002236268,0.0004317773,0.000007513104,0.4724756,0.0001904779,0.01175546,0.00003236415],"study_design_scores_gemma":[0.004912946,0.0006726913,0.7598171,0.003030212,0.002749473,0.000002286341,0.00003247593,0.0007192802,0.2144992,0.000001790654,0.01187298,0.001689578],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893723,0.005517547,0.0002050192,0.0009714416,0.0004834248,0.001016486,0.002017024,0.0003890816,0.00002764692],"genre_scores_gemma":[0.9959176,0.001407716,0.0007782397,0.001283662,0.0002755147,0.0001212823,0.000009464362,0.0001537135,0.0000527777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2606377,"threshold_uncertainty_score":0.9997151,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008955093291576021,"score_gpt":0.2037235659238986,"score_spread":0.1947684726323226,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}