{"id":"W3171764919","doi":"10.3389/fimmu.2021.666370","title":"lncRNA-HEIM Facilitated Liver Fibrosis by Up-Regulating TGF-β Expression in Long-Term Outcome of Chronic Hepatitis B","year":2021,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Major Science and Technology Projects of China; National Key Research and Development Program of China","keywords":"Biology; Hepatitis B virus; Hepatitis B; RNA interference; Immune system; Peripheral blood mononuclear cell; Cancer research; Immunology; RNA; Virology; Molecular biology; Virus; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001701293,0.0001517696,0.0001890298,0.0001833809,0.000160719,0.0002139208,0.0000847315,0.0001081964,0.001889744],"category_scores_gemma":[0.0001803699,0.00005994032,0.0001995544,0.0002277306,0.0001625151,0.0001027024,0.000232897,0.0002362982,0.0002080828],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000126768,"about_ca_system_score_gemma":0.0001694749,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003170384,"about_ca_topic_score_gemma":0.0005366855,"domain_scores_codex":[0.9999197,0.00001244754,0.000007026229,0.00002286917,0.00001544128,0.00002244687],"domain_scores_gemma":[0.9998748,0.00002099466,0.00005083517,0.000009938677,0.0000144637,0.00002905464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003805272,0.0001426989,0.1260529,0.0003220361,0.0001089046,0.0005321029,0.0002009261,0.0004361147,0.8426765,0.000273321,0.0003991625,0.0250502],"study_design_scores_gemma":[0.00008350808,0.001493813,0.8036733,0.00004501014,0.0002781386,0.001334733,0.0004109665,0.003264878,0.1839989,0.0004947711,0.004894678,0.00002734668],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974246,0.0008231024,0.0008062935,0.00004304261,0.00001120121,0.000008888828,0.000356486,0.00003462043,0.000491899],"genre_scores_gemma":[0.9980175,0.0002410491,0.0005321836,0.00004966753,0.00001037335,0.00001592893,0.0003327416,0.000008940212,0.000791473],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001889744,"threshold_uncertainty_score":0.006321788,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008503391459922788,"score_gpt":0.2566552484542463,"score_spread":0.2481518569943235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}