{"id":"W3171841707","doi":"10.2139/ssrn.3606298","title":"High Dimensional Single-Cell Analysis Reveals iNKT Cell Developmental Trajectories and Effector Fate Decision","year":2020,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"Effector; Cell fate determination; Cell biology; Cell; Biology; Genetics; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006795915,0.00009982089,0.0001911843,0.0002423592,0.0002215744,0.0008259094,0.0001729346,0.0002618561,0.00148169],"category_scores_gemma":[0.00009870557,0.000172777,0.0001901026,0.0002612337,0.0001757225,0.0002507613,0.0001950284,0.0006152106,0.0009405758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003436088,"about_ca_system_score_gemma":0.0001702283,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006596592,"about_ca_topic_score_gemma":0.001982221,"domain_scores_codex":[0.999945,0.000003983179,0.000005062795,0.00001544166,0.00001984387,0.0000107926],"domain_scores_gemma":[0.9999101,0.00003273378,0.000016697,0.0000145991,0.00001215322,0.00001366964],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00004847234,0.000006359959,0.0008506756,0.0000124685,0.000002698969,0.00005466247,0.00002614029,0.0003791911,0.9965839,0.0002795943,0.0000610125,0.001694772],"study_design_scores_gemma":[0.000006402159,0.00003565876,0.02472236,0.000004653305,0.00001271962,0.0003653728,0.0001037676,0.01054488,0.9613811,0.0003759213,0.002436195,0.00001083889],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9758507,0.0007527449,0.01834557,0.0001082208,0.00003194527,0.00001308149,0.001255286,0.0002140482,0.003428425],"genre_scores_gemma":[0.9802582,0.0006611812,0.01286555,0.00005637421,0.00001037014,0.00003237151,0.001159509,0.0001122751,0.004844091],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00148169,"threshold_uncertainty_score":0.004956722,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007343153125053025,"score_gpt":0.2007770568943354,"score_spread":0.1934339037692824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}