{"id":"W3171902846","doi":"10.3390/curroncol28030200","title":"Dual Targeting of Sorafenib-Resistant HCC-Derived Cancer Stem Cells","year":2021,"lang":"en","type":"article","venue":"Current Oncology","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Sorafenib; Cancer research; Cancer stem cell; Population; Medicine; Immune checkpoint; Cancer; Side population; Immunology; Hepatocellular carcinoma; Internal medicine; Immunotherapy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001204989,0.0002014316,0.0003770647,0.000209188,0.00007313939,0.0002856854,0.0001326647,0.0001621988,0.00100378],"category_scores_gemma":[0.00007228315,0.00007997581,0.0001922341,0.0001267097,0.00008843793,0.0001208007,0.0001351286,0.0002935832,0.0002115378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002122821,"about_ca_system_score_gemma":0.0001839406,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003714377,"about_ca_topic_score_gemma":0.0008021165,"domain_scores_codex":[0.9998767,0.00002037733,0.000008461852,0.00001993749,0.00004889539,0.00002554975],"domain_scores_gemma":[0.9999628,0.000006923392,0.000006629054,0.000004426961,0.000007118491,0.00001203927],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003339262,0.0001250554,0.0002245987,0.0001019383,0.0000154836,0.00006899773,0.00002562451,0.0002916744,0.9905777,0.0002564814,0.0001993473,0.007779263],"study_design_scores_gemma":[0.00008839851,0.001074536,0.002372067,0.000004708204,0.00004457454,0.0003226143,0.00002307069,0.003808193,0.9867006,0.00004420606,0.005510957,0.000005978032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915529,0.001330143,0.004284284,0.0000811526,0.00003983012,0.00009419974,0.0002651405,0.00009568892,0.002256691],"genre_scores_gemma":[0.9946734,0.0004741426,0.002162734,0.00003377498,0.00000989926,0.00005514649,0.0003764178,0.0000104012,0.002204197],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00100378,"threshold_uncertainty_score":0.003357947,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1121711372595805,"score_gpt":0.396535664641986,"score_spread":0.2843645273824056,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}