{"id":"W3172218068","doi":"10.1016/j.celrep.2021.109208","title":"Generation of excitatory and inhibitory neurons from common progenitors via Notch signaling in the cerebellum","year":2021,"lang":"en","type":"article","venue":"Cell Reports","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"European Research Council; Horizon 2020 Framework Programme; China Scholarship Council; Fondation pour la Recherche Médicale; Associazione Italiana per la Ricerca sul Cancro; Sorbonne Université; Berlin Institute of Health; Association Sorbonne Université; Agence Nationale de la Recherche; Fondation Roger de Spoelberch; Institut de Cardiologie de Montréal; European Commission; Österreichischen Akademie der Wissenschaften; Giovanni Armenise-Harvard Foundation; Paul G. Allen Family Foundation","keywords":"Inhibitory postsynaptic potential; Neurogenesis; Excitatory postsynaptic potential; Progenitor cell; Notch signaling pathway; Biology; Progenitor; Neuroscience; Cell fate determination; Cerebellum; Cell biology; Stem cell; Signal transduction; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002498032,0.0002011445,0.0003044019,0.0004171651,0.0001852863,0.0006540714,0.0003282264,0.0001902975,0.0002691323],"category_scores_gemma":[0.0002044001,0.0002500227,0.000148634,0.0001862941,0.0003463079,0.0003645692,0.0006215193,0.0003872265,0.000146999],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004776494,"about_ca_system_score_gemma":0.0002835525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007807852,"about_ca_topic_score_gemma":0.002509413,"domain_scores_codex":[0.9998164,0.00001870857,0.00002118314,0.00004204968,0.00007572443,0.00002605429],"domain_scores_gemma":[0.9998702,0.00001739248,0.00003913251,0.0000125462,0.000009324752,0.00005146369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006753091,0.00001467578,0.001315034,0.00002534915,0.000005954563,0.0001115136,0.00004574598,0.0001594718,0.9940898,0.0009215135,0.00001789966,0.003225526],"study_design_scores_gemma":[0.00004417769,0.000186524,0.02370006,0.00002882515,0.00004283703,0.000701161,0.0001263877,0.004094053,0.9682888,0.0009286794,0.001844936,0.00001356989],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942059,0.0007205671,0.003607831,0.00002845108,0.000005573189,0.00001012846,0.00006794729,0.00002576668,0.001327866],"genre_scores_gemma":[0.9966837,0.0003751363,0.002007036,0.00001186859,0.000001877429,0.00000735438,0.00006864695,0.000007817579,0.0008365703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007807852,"threshold_uncertainty_score":0.003465652,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05169960353838878,"score_gpt":0.2475043262280044,"score_spread":0.1958047226896157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}