{"id":"W3172271359","doi":"10.1016/j.chom.2021.06.001","title":"A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses","year":2021,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":208,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut National de Santé Publique du Québec; Université du Québec à Montréal; McGill University Health Centre; Université de Montréal; McGill University; Centre Hospitalier de l’Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; National Institutes of Health; Canada Excellence Research Chairs, Government of Canada; Fondation du CHUM; Canada Foundation for Innovation; National Institute of Allergy and Infectious Diseases; Ministère de l'Économie, de l’Innovation et des Exportations du Québec; Canadian Institutes of Health Research; Mitacs; Genome Canada","keywords":"Biology; Effector; Antibody; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Virology; Coronavirus disease 2019 (COVID-19); 2019-20 coronavirus outbreak; Antibody response; Immunology; Computational biology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003278028,0.0002873469,0.0004941341,0.0002064345,0.0001771607,0.00005368645,0.0002117562,0.0001963113,0.00004323826],"category_scores_gemma":[0.0004642513,0.0002158484,0.0002046219,0.0009571047,0.0001555588,0.00007320438,0.0003085256,0.0004377619,0.0003770621],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008945783,"about_ca_system_score_gemma":0.0004991111,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002011681,"about_ca_topic_score_gemma":0.0001207654,"domain_scores_codex":[0.9979718,0.000272322,0.0004037363,0.000525717,0.0003356205,0.0004907912],"domain_scores_gemma":[0.9980447,0.0005898608,0.0001381805,0.0007935859,0.0003731111,0.00006057217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008872271,0.0007807726,0.02154357,0.0004390659,0.00005382119,0.0001557429,0.0003312697,7.745052e-8,0.9680184,9.564956e-7,0.007489317,0.0002997844],"study_design_scores_gemma":[0.002948159,0.0004356842,0.01630701,0.0001575667,0.00012561,0.0001051988,0.0001593742,0.00002080163,0.7996429,0.000001966732,0.1799305,0.0001652504],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902691,0.005159329,0.00002798245,0.0005840581,0.0003012172,0.0006189324,0.0001943638,0.0000649431,0.002780061],"genre_scores_gemma":[0.9880966,0.00006744533,0.00008254386,0.01012881,0.0001496185,0.00001933005,0.00007603152,0.0000642893,0.001315328],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1724412,"threshold_uncertainty_score":0.8802041,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02465531015574523,"score_gpt":0.3126658280068103,"score_spread":0.288010517851065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}