{"id":"W3172271359","doi":"10.1016/j.chom.2021.06.001","title":"A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and T cell responses","year":2021,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":208,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut National de Santé Publique du Québec; Université du Québec à Montréal; McGill University Health Centre; Université de Montréal; McGill University; Centre Hospitalier de l’Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; National Institutes of Health; Canada Excellence Research Chairs, Government of Canada; Fondation du CHUM; Canada Foundation for Innovation; National Institute of Allergy and Infectious Diseases; Ministère de l'Économie, de l’Innovation et des Exportations du Québec; Canadian Institutes of Health Research; Mitacs; Genome Canada","keywords":"Biology; Effector; Antibody; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Virology; Coronavirus disease 2019 (COVID-19); 2019-20 coronavirus outbreak; Antibody response; Immunology; Computational biology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003760958,0.0009818485,0.0009606687,0.0003274157,0.000308155,0.0004039363,0.0002239079,0.001039494,0.002608343],"category_scores_gemma":[0.0003149192,0.0002831635,0.0003856555,0.0001700888,0.0003405595,0.0004089967,0.0003094914,0.002892765,0.000865858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000464638,"about_ca_system_score_gemma":0.000487047,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007327851,"about_ca_topic_score_gemma":0.001306395,"domain_scores_codex":[0.9995634,0.0000622278,0.00002335237,0.00007962588,0.0000805565,0.0001907977],"domain_scores_gemma":[0.9998049,0.00006129896,0.00002096216,0.00001994053,0.00001952108,0.00007332167],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002658029,0.001912766,0.0004493017,0.00009826069,0.00002086488,0.0001318655,0.00005919233,0.0005100105,0.9893641,0.0001198776,0.0004520608,0.004223575],"study_design_scores_gemma":[0.001238818,0.0388451,0.01546061,0.00004748636,0.00009292059,0.0007627002,0.0002547971,0.006404056,0.9312785,0.0003640667,0.005220063,0.00003091441],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946474,0.0004787821,0.001015439,0.0001797965,0.0002092506,0.0002186642,0.0005060001,0.00007228095,0.002672356],"genre_scores_gemma":[0.992533,0.0003288716,0.001230486,0.0002645459,0.0001123512,0.0001553309,0.0009678968,0.00002287452,0.004384502],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002608343,"threshold_uncertainty_score":0.008725703,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02465531015574523,"score_gpt":0.3126658280068103,"score_spread":0.288010517851065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}