{"id":"W3172303857","doi":"10.3390/cancers13122953","title":"CUT Domain Proteins in DNA Repair and Cancer","year":2021,"lang":"en","type":"review","venue":"Cancers","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"DNA repair; DNA damage; Cancer cell; Base excision repair; Cancer research; Gene knockdown; Biology; Cancer; Cell biology; KRAS; DNA repair protein XRCC4; Cisplatin; DNA; Chemistry; Nucleotide excision repair; Biochemistry; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005135424,0.001160077,0.001088901,0.002015291,0.0003374648,0.00106002,0.0009880592,0.001400849,0.004066523],"category_scores_gemma":[0.0004907086,0.0003045831,0.0003871841,0.002101485,0.0006905543,0.001636386,0.001035648,0.002144481,0.003115618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009199664,"about_ca_system_score_gemma":0.001056565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009320714,"about_ca_topic_score_gemma":0.001424244,"domain_scores_codex":[0.9998251,0.00002531065,0.0000210185,0.00003375917,0.00006992328,0.00002492124],"domain_scores_gemma":[0.999803,0.00007204283,0.00002581603,0.000008466523,0.00005799879,0.00003258936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007529766,0.00007396157,0.0001335267,0.009366911,0.00005678808,0.000240458,0.00006289352,0.0005315304,0.002524889,0.008081728,0.05303421,0.9258178],"study_design_scores_gemma":[0.000008878228,0.00004340121,0.0003030371,0.001163586,0.00002441267,0.0006949375,0.00002332982,0.00003419852,0.0002849503,0.002498753,0.9949117,0.000008852991],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005108787,0.9984071,0.00008790103,0.0002173985,0.0002467546,0.000002320473,0.000007372241,0.000007343192,0.0009728746],"genre_scores_gemma":[0.0005004269,0.99779,0.0001200818,0.0001847091,0.0001894048,0.000004409905,0.00002783852,0.000001607052,0.001181551],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004066523,"threshold_uncertainty_score":0.01360387,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02002670735198611,"score_gpt":0.306580515571334,"score_spread":0.2865538082193478,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}