{"id":"W3172303857","doi":"10.3390/cancers13122953","title":"CUT Domain Proteins in DNA Repair and Cancer","year":2021,"lang":"en","type":"review","venue":"Cancers","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"DNA repair; DNA damage; Cancer cell; Base excision repair; Cancer research; Gene knockdown; Biology; Cancer; Cell biology; KRAS; DNA repair protein XRCC4; Cisplatin; DNA; Chemistry; Nucleotide excision repair; Biochemistry; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001622142,0.0003011797,0.0007326484,0.00006074911,0.00002982951,0.00001680192,0.0001592828,0.0003951107,0.00004783753],"category_scores_gemma":[0.00003895703,0.0002834425,0.0002709423,0.0001632497,0.00006183232,0.000001874758,0.0001650897,0.0001892794,0.000003142809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005221517,"about_ca_system_score_gemma":0.001985235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001986814,"about_ca_topic_score_gemma":0.0007801364,"domain_scores_codex":[0.9985207,0.0001245214,0.0002917153,0.0006753676,0.0001039974,0.0002837394],"domain_scores_gemma":[0.9992674,0.000007245002,0.0001350859,0.000468419,0.00003095384,0.000090922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001433293,0.00001598559,0.00001416387,0.009554099,0.0003991499,0.0001224455,0.00006493877,0.000008563629,0.001832574,0.0002218373,0.005533961,0.982218],"study_design_scores_gemma":[0.0001666204,0.00005307095,5.717488e-7,0.004116607,0.00008864146,0.00002428956,0.00002690878,0.000001849759,0.000932926,0.0000167697,0.9942552,0.0003165512],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007127443,0.9975587,0.00001645593,0.00001150769,0.0002836641,0.0007202513,0.00007076404,0.00002240925,0.0006035033],"genre_scores_gemma":[0.00001598572,0.996426,0.0006187495,0.00009578389,0.0002711919,0.0008888949,0.0001367963,0.0000608731,0.001485742],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9887213,"threshold_uncertainty_score":0.9999618,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02002670735198611,"score_gpt":0.306580515571334,"score_spread":0.2865538082193478,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}