{"id":"W3172413452","doi":"10.1200/jco.2021.39.15_suppl.9509","title":"Overall survival benefit from tebentafusp in patients with best response of progressive disease.","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"","keywords":"Medicine; Internal medicine; Cohort; Pembrolizumab; Progressive disease; Oncology; Interim analysis; Randomized controlled trial; Disease; Nuclear medicine; Cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001041533,0.0002071589,0.0005744236,0.0001918896,0.0001327172,0.0003088438,0.0001919301,0.0002921996,0.002103898],"category_scores_gemma":[0.000975502,0.00009092621,0.0005397476,0.000173773,0.00020569,0.0002840222,0.0001982751,0.0006952304,0.0002128666],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004362606,"about_ca_system_score_gemma":0.000331729,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003471735,"about_ca_topic_score_gemma":0.0009779013,"domain_scores_codex":[0.9997224,0.0001104892,0.00001687894,0.00005859793,0.00003735482,0.0000542657],"domain_scores_gemma":[0.9995081,0.0001817413,0.0001123866,0.00004134965,0.00001932515,0.000137064],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.6083868,0.004264306,0.1162279,0.000778746,0.001472735,0.0003748821,0.000183662,0.004234463,0.02767606,0.0004912801,0.004799234,0.23111],"study_design_scores_gemma":[0.09506982,0.362557,0.5080522,0.0002180566,0.002892427,0.002099886,0.0001400447,0.005295405,0.01008499,0.001308131,0.01223821,0.00004385091],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956327,0.002112638,0.0002545474,0.0001417302,0.00001928414,0.00009495446,0.0005281643,0.00001430739,0.001201623],"genre_scores_gemma":[0.9984347,0.0003113431,0.0001601121,0.0001231832,0.00002400708,0.00005967431,0.0005876123,0.000003103979,0.0002961891],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002103898,"threshold_uncertainty_score":0.007038236,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07157264237981696,"score_gpt":0.4179175306840169,"score_spread":0.3463448883041999,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}