{"id":"W3172530387","doi":"10.1093/ndt/gfab092.00108","title":"MO230A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED STUDY OF ATRASENTAN IN PATIENTS WITH IGA NEPHROPATHY (THE ALIGN STUDY)","year":2021,"lang":"en","type":"article","venue":"Nephrology Dialysis Transplantation","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Proteinuria; Kidney disease; Renal function; Nephropathy; Internal medicine; Placebo; Gastroenterology; Urology; Creatinine; Kidney; Diabetes mellitus; Endocrinology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001710574,0.001550092,0.003008232,0.0003493488,0.0004680141,0.001269293,0.0008082696,0.001978934,0.006563789],"category_scores_gemma":[0.0009920539,0.0004742599,0.002039435,0.0003076627,0.0007514399,0.000811473,0.0003124186,0.002790916,0.001149384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005086993,"about_ca_system_score_gemma":0.0009837211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007562743,"about_ca_topic_score_gemma":0.001901154,"domain_scores_codex":[0.9994548,0.0002694624,0.00002968226,0.0001092233,0.00004459797,0.00009228804],"domain_scores_gemma":[0.9993493,0.0001113433,0.0001788331,0.00004565925,0.0000567862,0.0002581012],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9421513,0.01139975,0.0009638394,0.001607645,0.002737632,0.00008820154,0.00005356596,0.0002571017,0.008247678,0.000146261,0.002999552,0.0293474],"study_design_scores_gemma":[0.9307796,0.06453861,0.002479244,0.00004927447,0.0004969218,0.00005199197,0.0000170121,0.0001873549,0.0003724298,0.0001091076,0.0009003636,0.0000181336],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9592679,0.02669757,0.001036456,0.00137555,0.0009993264,0.004315952,0.002054807,0.0004885428,0.003763919],"genre_scores_gemma":[0.9747908,0.007634208,0.002438727,0.003839693,0.0009357557,0.004409083,0.001596718,0.0000502087,0.004304788],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006563789,"threshold_uncertainty_score":0.02195805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01255771739587668,"score_gpt":0.2815244840935816,"score_spread":0.2689667666977049,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}