{"id":"W3172614171","doi":"10.1007/s00213-021-05867-y","title":"Reduced cortical GABA and glutamate in high schizotypy","year":2021,"lang":"en","type":"article","venue":"Psychopharmacology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Krembil Foundation; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; University of Roehampton","keywords":"Schizotypy; Psychology; Glutamate receptor; Schizophrenia (object-oriented programming); Prefrontal cortex; Psychosis; Neuroscience; Metabolite; Neurotransmitter; Dopamine; gamma-Aminobutyric acid; Internal medicine; Psychiatry; Endocrinology; Medicine; Central nervous system; Cognition","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002794771,0.0001873374,0.0002814499,0.0002317395,0.0002135893,0.00005242326,0.0003266222,0.0001058087,0.0009860492],"category_scores_gemma":[0.0005686288,0.0001881219,0.00004268504,0.0009374739,0.0005874168,0.0001881909,0.0002444583,0.000836147,0.0002614945],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002922865,"about_ca_system_score_gemma":0.0001452672,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003841903,"about_ca_topic_score_gemma":0.000005009511,"domain_scores_codex":[0.9967422,0.000939702,0.0003223399,0.0009905952,0.0002578956,0.0007472615],"domain_scores_gemma":[0.9986956,0.000720028,0.00005393157,0.0002199571,0.00004098929,0.0002694749],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003155357,0.0002770652,0.002295681,0.00001262893,0.000002641781,0.002637001,0.00003848075,0.000005866246,0.9915313,0.001052402,0.0008024476,0.001028912],"study_design_scores_gemma":[0.003307499,0.0001600357,0.02513913,0.000005810492,0.00001159889,0.0006176322,0.00001492166,0.0003613041,0.9672366,0.0006993865,0.002252345,0.0001937584],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907123,0.0001340633,0.00000509638,0.005580893,0.00192736,0.000253517,0.00001286698,0.00007579147,0.001298085],"genre_scores_gemma":[0.988405,0.001150029,0.00003933313,0.009474173,0.0001171474,0.00006171672,5.061303e-7,0.00002436837,0.0007277194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02429475,"threshold_uncertainty_score":0.9999272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04590377707536233,"score_gpt":0.383613736922516,"score_spread":0.3377099598471537,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}