{"id":"W3172666746","doi":"10.21203/rs.3.rs-563215/v1","title":"ANRIL Regulates Multiple Molecules of Pathogenetic Significance in Diabetic Nephropathy","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; London Health Sciences Centre; Ontario Institute for Cancer Research","funders":"","keywords":"Diabetic nephropathy; Long non-coding RNA; Diabetes mellitus; Albuminuria; Polyuria; Knockout mouse; Biology; Type 2 diabetes; Epigenetics; Endocrinology; Internal medicine; Cell biology; RNA; Medicine; Gene; Receptor; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001968522,0.0003725269,0.0003098185,0.0003725759,0.0002847554,0.0005114173,0.0001551484,0.0002405789,0.00180432],"category_scores_gemma":[0.0001090159,0.0001257742,0.0004329493,0.0002843173,0.0001507366,0.0002447533,0.0003269768,0.0003988194,0.0002635258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002648586,"about_ca_system_score_gemma":0.000178546,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002658138,"about_ca_topic_score_gemma":0.0002601009,"domain_scores_codex":[0.9998586,0.00002295872,0.00001045184,0.00004973658,0.00003408855,0.00002408524],"domain_scores_gemma":[0.9998398,0.00002006091,0.00007530398,0.000007101194,0.0000230563,0.00003468407],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009246273,0.0001345567,0.01344409,0.0007787346,0.0001960123,0.0004989582,0.00008545327,0.0009790373,0.9695064,0.0008968015,0.0008854672,0.01166986],"study_design_scores_gemma":[0.0001694308,0.001279121,0.548939,0.0002874493,0.0009129098,0.00181895,0.0004402248,0.01774039,0.3928244,0.003403855,0.03208793,0.00009631404],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9575294,0.01977597,0.01250203,0.0005186232,0.0002061033,0.00007521111,0.003736231,0.0004253541,0.005231],"genre_scores_gemma":[0.9827967,0.00557009,0.005168481,0.0002267824,0.00007834745,0.00006745019,0.002527985,0.00003467878,0.003529342],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00180432,"threshold_uncertainty_score":0.006036043,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02659114228560162,"score_gpt":0.3320908328445468,"score_spread":0.3054996905589452,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}