{"id":"W3172703328","doi":"10.1093/ndt/gfab121.004","title":"FC 035VOCLOSPORIN INCREASES RENAL RESPONSE AT COMMONLY USED UPCR THRESHOLDS IN PATIENTS WITH LUPUS NEPHRITIS","year":2021,"lang":"en","type":"article","venue":"Nephrology Dialysis Transplantation","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Aurinia (Canada)","funders":"","keywords":"Medicine; Proteinuria; Urology; Clinical endpoint; Lupus nephritis; Post-hoc analysis; Calcineurin; Renal function; Regimen; Internal medicine; Placebo; Surrogate endpoint; Pharmacology; Randomized controlled trial; Kidney; Transplantation; Disease; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005970369,0.0003448262,0.001012585,0.0004786313,0.0002364273,0.0008546094,0.0003351066,0.00056469,0.001498786],"category_scores_gemma":[0.008800433,0.0002149377,0.002175888,0.0005269525,0.0002413876,0.0004106217,0.0003242698,0.0007709158,0.0001323932],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004984159,"about_ca_system_score_gemma":0.0003932791,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008175541,"about_ca_topic_score_gemma":0.0008189892,"domain_scores_codex":[0.9953502,0.002820454,0.0003217371,0.0006757141,0.0005659903,0.00026574],"domain_scores_gemma":[0.9913618,0.005019273,0.002357979,0.0006497235,0.0002678377,0.0003434076],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.08202133,0.0006780576,0.8685551,0.0004703341,0.006965926,0.0002679208,0.0001031706,0.003375884,0.005436766,0.0001527141,0.0006998017,0.03127304],"study_design_scores_gemma":[0.003289651,0.01540839,0.9635322,0.00009956254,0.004535545,0.0007985376,0.00008647726,0.005442794,0.004615703,0.0004902743,0.001648291,0.00005246712],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958907,0.002371383,0.0003327543,0.00008849207,0.00001762377,0.00006832877,0.0004357891,0.00002198196,0.000772916],"genre_scores_gemma":[0.9994195,0.00008887374,0.0002042193,0.00005108444,0.00001375345,0.00002416296,0.0001500718,0.000002001008,0.00004649682],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005970369,"threshold_uncertainty_score":0.03157473,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01260881587733374,"score_gpt":0.2570968531841869,"score_spread":0.2444880373068532,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}