{"id":"W3172799802","doi":"10.1096/fasebj.24.1_supplement.770.3","title":"Potassium Channel Block by a Tripartite Complex of Neutral Ligands with a Potassium Ion","year":2010,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; National Institutes of Health; Howard Hughes Medical Institute","keywords":"Chemistry; Linker; Potassium channel; Ion channel; Stereochemistry; Homology modeling; Cationic polymerization; Biophysics; Crystallography; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002620124,0.0003664311,0.0002338333,0.0001215696,0.0001943845,0.0002931108,0.0005564886,0.0004048142,0.001826677],"category_scores_gemma":[0.0004719995,0.0001859289,0.0002525946,0.0001182319,0.0003200889,0.0002996352,0.0004164338,0.0005355727,0.0004911286],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009352237,"about_ca_system_score_gemma":0.0004057484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001042451,"about_ca_topic_score_gemma":0.001079158,"domain_scores_codex":[0.9996432,0.0000980267,0.00002578371,0.00006026765,0.00009703538,0.00007575046],"domain_scores_gemma":[0.9997463,0.00003895839,0.00006873927,0.00004198478,0.00002603136,0.0000780312],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000341357,0.00007949871,0.000378736,0.0000467429,0.00004076813,0.00008767948,0.00001952429,0.0004994814,0.9966307,0.0003865336,0.0001786701,0.001310269],"study_design_scores_gemma":[0.0002254001,0.001233215,0.00505399,0.00001979083,0.00009649858,0.0008845555,0.00004207878,0.01972324,0.9672636,0.0003298142,0.005096058,0.00003172858],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997022,0.0001885464,0.002030246,0.00008348673,0.00002214525,0.00001654129,0.00006096212,0.00004896216,0.000527065],"genre_scores_gemma":[0.9957057,0.0001028745,0.002866356,0.00008038929,0.000006064402,0.00002129808,0.0002277311,0.00001666408,0.000972953],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001826677,"threshold_uncertainty_score":0.006785572,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009867681125723232,"score_gpt":0.2468285196961043,"score_spread":0.2369608385703811,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}