{"id":"W3172860414","doi":"10.1093/biolre/ioab113","title":"Self-renewal and differentiation of rat epididymal basal cells using a novel in vitro organoid model","year":2021,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Clusterin in disease pathology","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Fonds de recherche du Québec – Nature et technologies; Canadian Institutes of Health Research","keywords":"Organoid; Biology; Cell biology; Epididymis; Stem cell; Basal (medicine); Cellular differentiation; Clusterin; Cell type; Cell; In vitro; Cell culture; Endocrinology; Biochemistry; Genetics; Apoptosis; Sperm","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005680348,0.0005861514,0.0005733548,0.0005644175,0.000361889,0.0007130638,0.0008087996,0.0006111495,0.0008659364],"category_scores_gemma":[0.0002111529,0.000284451,0.0008497832,0.0003760335,0.0003315007,0.0004767585,0.0005697591,0.001413516,0.0007221131],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004271073,"about_ca_system_score_gemma":0.0004752578,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001736618,"about_ca_topic_score_gemma":0.002165661,"domain_scores_codex":[0.9996132,0.00004999073,0.00005308216,0.00009832392,0.0001389001,0.000046501],"domain_scores_gemma":[0.9996313,0.00005604621,0.00005828484,0.00009725258,0.00006465216,0.00009243339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000751328,0.00007158119,0.0003950035,0.00007870749,0.000009307905,0.000203042,0.00008748058,0.0004525769,0.9969374,0.0002961259,0.00005483121,0.001338946],"study_design_scores_gemma":[0.00002120054,0.0006485451,0.002969018,0.00002582936,0.00005990993,0.0006524795,0.0001022124,0.003142066,0.9847918,0.0001109108,0.007459657,0.00001638337],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9029903,0.00559809,0.08149132,0.0003095803,0.0002038278,0.0004772952,0.001934669,0.0003859609,0.006608868],"genre_scores_gemma":[0.9360917,0.004304517,0.04753604,0.000138218,0.0000371688,0.0004113492,0.002909353,0.00006792769,0.008503656],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001736618,"threshold_uncertainty_score":0.003453076,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03054328762095357,"score_gpt":0.2852126668420072,"score_spread":0.2546693792210536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}