{"id":"W3173004643","doi":"10.3390/clockssleep3020020","title":"Cellular Effects of Rhynchophylline and Relevance to Sleep Regulation","year":2021,"lang":"en","type":"review","venue":"Clocks & Sleep","topic":"Sleep and Wakefulness Research","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Sleep & Circadian Network; Université de Montréal; Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal","funders":"","keywords":"MAPK/ERK pathway; Kinase; PI3K/AKT/mTOR pathway; Receptor tyrosine kinase; Signal transduction; Protein kinase B; Sleep (system call); Protein kinase A; Pharmacology; Neuroscience; Biology; Medicine; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001608478,0.0005798303,0.0005759326,0.001212226,0.0001934264,0.0005454292,0.0004177224,0.0005290721,0.002183965],"category_scores_gemma":[0.0001814556,0.0001550662,0.0002247354,0.001157156,0.0002604448,0.0007395297,0.0004431557,0.0007531479,0.001359026],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000426175,"about_ca_system_score_gemma":0.0005305502,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0010904,"about_ca_topic_score_gemma":0.001916365,"domain_scores_codex":[0.9999568,0.000006054546,0.000006053956,0.00001126494,0.00001307731,0.000006688771],"domain_scores_gemma":[0.9999461,0.00001701201,0.00001015603,0.000001927588,0.00001737089,0.000007385141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001146975,0.00005645443,0.0002040833,0.01871349,0.00005819462,0.0003788556,0.0001147441,0.0004789752,0.01510779,0.005813561,0.01552474,0.9434345],"study_design_scores_gemma":[0.0000138157,0.0001235168,0.001626628,0.001750321,0.0000703219,0.001307343,0.00007146345,0.00009884545,0.002354218,0.002318492,0.9902474,0.00001761137],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002911671,0.9981382,0.00009956756,0.0001057823,0.00009208889,0.000003279148,0.00002132067,0.000005898595,0.0012426],"genre_scores_gemma":[0.001804048,0.9969674,0.0001333883,0.00009126628,0.00007295547,0.000005675612,0.00003747783,0.000001372216,0.0008864648],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002183965,"threshold_uncertainty_score":0.007306099,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03698130142682071,"score_gpt":0.3285095147104211,"score_spread":0.2915282132836003,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}