{"id":"W3173004643","doi":"10.3390/clockssleep3020020","title":"Cellular Effects of Rhynchophylline and Relevance to Sleep Regulation","year":2021,"lang":"en","type":"review","venue":"Clocks & Sleep","topic":"Sleep and Wakefulness Research","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Sleep & Circadian Network; Université de Montréal; Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal","funders":"","keywords":"MAPK/ERK pathway; Kinase; PI3K/AKT/mTOR pathway; Receptor tyrosine kinase; Signal transduction; Protein kinase B; Sleep (system call); Protein kinase A; Pharmacology; Neuroscience; Biology; Medicine; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003106247,0.0004911866,0.001680624,0.0003536451,0.0001519257,0.00008140748,0.0005559968,0.000363109,0.00008049541],"category_scores_gemma":[0.003604985,0.000429918,0.0003449545,0.001386988,0.0001717711,0.0001109537,0.0004343262,0.0005683037,0.000114821],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009040417,"about_ca_system_score_gemma":0.00009683771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007739456,"about_ca_topic_score_gemma":0.000001788518,"domain_scores_codex":[0.996246,0.00060425,0.0007242323,0.001146588,0.000740973,0.0005379601],"domain_scores_gemma":[0.9958183,0.002433792,0.0003131678,0.001001775,0.0001411446,0.0002918831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000084436,0.00008051894,0.000002728187,0.010208,0.00002984786,0.0001259233,0.0000485895,0.00001833496,0.002650142,0.0005419916,0.0002485119,0.986037],"study_design_scores_gemma":[0.0003191288,0.0001640175,0.000006539338,0.007204781,0.0002797458,0.00003524159,0.000003722065,0.0002101834,0.04191302,0.0001401579,0.9492309,0.000492555],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001066912,0.994535,0.00166811,0.00004949066,0.0006779135,0.001437918,0.00002862499,0.00005846152,0.0004775488],"genre_scores_gemma":[0.004042589,0.9939869,0.0002012782,0.0000867749,0.0003499573,0.0002344662,0.00003508696,0.00009911313,0.0009638434],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9855444,"threshold_uncertainty_score":0.9998153,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03698130142682071,"score_gpt":0.3285095147104211,"score_spread":0.2915282132836003,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}