{"id":"W3173223047","doi":"10.3390/cancers13133157","title":"Docetaxel-Mediated Uptake and Retention of Gold Nanoparticles in Tumor Cells and in Cancer-Associated Fibroblasts","year":2021,"lang":"en","type":"article","venue":"Cancers","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia; University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; NanoMedicines Innovation Network","keywords":"Cancer-Associated Fibroblasts; Tumor microenvironment; Docetaxel; Cancer cell; Cancer research; Cancer; Cell culture; Chemistry; Tumor cells; Medicine; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003254933,0.0001165333,0.0002659874,0.00008679086,0.00002173356,0.00002980519,0.00006955263,0.00005224644,0.0000745449],"category_scores_gemma":[0.0001457048,0.0001240404,0.00002008571,0.0004860914,0.0001394645,0.0001957879,0.00005980732,0.00007788929,0.000004953375],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004937688,"about_ca_system_score_gemma":0.0003943596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002161935,"about_ca_topic_score_gemma":0.007185917,"domain_scores_codex":[0.9986966,0.0001200801,0.0003689536,0.0003325917,0.0001711337,0.0003106298],"domain_scores_gemma":[0.9994587,0.0001046047,0.0001385738,0.0001361555,0.00007496245,0.0000869689],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008345228,0.00003083974,0.009549405,0.00006925332,0.00000422491,0.00004582455,0.0002950838,0.001585876,0.9878893,0.00001045327,0.0001524171,0.0002838286],"study_design_scores_gemma":[0.001357318,0.00005026087,0.03276349,0.0002733406,0.00001270916,0.000002046714,0.0002724687,0.002287919,0.962729,0.00005513338,0.00006447951,0.0001318003],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976112,0.001779484,5.332039e-7,0.00009874962,0.0001933735,0.0001480627,0.0001155288,0.00002245346,0.00003057464],"genre_scores_gemma":[0.9993904,0.0003103541,0.0001053648,0.00008536205,0.00001183403,0.00002948893,0.000005674356,0.00001213085,0.00004934849],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02516031,"threshold_uncertainty_score":0.5058221,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01463831980953675,"score_gpt":0.2329597365185159,"score_spread":0.2183214167089791,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}