{"id":"W3173223047","doi":"10.3390/cancers13133157","title":"Docetaxel-Mediated Uptake and Retention of Gold Nanoparticles in Tumor Cells and in Cancer-Associated Fibroblasts","year":2021,"lang":"en","type":"article","venue":"Cancers","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia; University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; NanoMedicines Innovation Network","keywords":"Cancer-Associated Fibroblasts; Tumor microenvironment; Docetaxel; Cancer cell; Cancer research; Cancer; Cell culture; Chemistry; Tumor cells; Medicine; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001705089,0.0002637352,0.0001916828,0.0001148194,0.0001458994,0.0002045512,0.0001035231,0.0001675254,0.0003894611],"category_scores_gemma":[0.0001146334,0.0001000845,0.0001656806,0.0001269627,0.0001645042,0.000137864,0.000097261,0.0001838824,0.0001409636],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003942643,"about_ca_system_score_gemma":0.0002251143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005068701,"about_ca_topic_score_gemma":0.004177639,"domain_scores_codex":[0.9998709,0.00002449903,0.00001115855,0.00004120127,0.00002834461,0.0000237816],"domain_scores_gemma":[0.9999433,0.00002196705,0.0000105448,0.000005847701,0.000009347515,0.000009173609],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005087442,0.00001244528,0.0002171701,0.00003802513,0.000002713728,0.00006046392,0.00004399506,0.00009423579,0.9984192,0.00004550175,0.00002404095,0.0009914672],"study_design_scores_gemma":[0.000005663461,0.0001157659,0.001856117,0.000002080675,0.00000750042,0.0001107162,0.00002683746,0.0006875055,0.9964881,0.00001303406,0.0006825035,0.000004282734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947059,0.001536723,0.002364281,0.0000375507,0.00001970982,0.00001844812,0.0001449113,0.00002826434,0.001144298],"genre_scores_gemma":[0.9936393,0.001046396,0.002504076,0.00002327071,0.000004500473,0.00002706451,0.000119849,0.00001088336,0.002624634],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005068701,"threshold_uncertainty_score":0.01007837,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01463831980953675,"score_gpt":0.2329597365185159,"score_spread":0.2183214167089791,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}