{"id":"W3173254765","doi":"10.1101/2021.06.18.448928","title":"Single-cell RNA sequencing-based characterization of resident lung mesenchymal stromal cells in bronchopulmonary dysplasia","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Eastern Ontario; Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research; Lastentautien Tutkimussäätiö; Deutsche Forschungsgemeinschaft; Canadian Lung Association","keywords":"Mesenchymal stem cell; Bronchopulmonary dysplasia; Lung; Hyperoxia; Transcriptome; Population; Stromal cell; Biology; Immunology; Medicine; Pathology; Cancer research; Gene expression; Gene; Gestational age; Genetics; Internal medicine; Pregnancy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002072506,0.0002311617,0.0002633046,0.000611771,0.0002008708,0.0003312527,0.0001643319,0.0002745206,0.0006775861],"category_scores_gemma":[0.0002990097,0.0001249495,0.0002432433,0.0003242609,0.0001796242,0.00009739827,0.0001580652,0.0002129986,0.0003428076],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001295142,"about_ca_system_score_gemma":0.0001708975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005116618,"about_ca_topic_score_gemma":0.001096596,"domain_scores_codex":[0.9998473,0.0000139681,0.00001270283,0.00005081253,0.0000558214,0.00001935813],"domain_scores_gemma":[0.9997914,0.00005783297,0.00006142559,0.00001480914,0.00005010389,0.00002452944],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004811026,0.000006890362,0.002248477,0.00005213009,0.000007888652,0.00006866769,0.00002956074,0.0001713262,0.9948279,0.00002820891,0.0000440219,0.002466718],"study_design_scores_gemma":[0.00001252488,0.0002945516,0.1282514,0.00004098971,0.00008904618,0.001175157,0.0003053359,0.009826832,0.8534611,0.0002867579,0.006231888,0.00002435481],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9688823,0.001419016,0.02261631,0.00008097089,0.00003764842,0.00006490192,0.005571146,0.0002252813,0.001102498],"genre_scores_gemma":[0.9598808,0.0009879841,0.03011593,0.0001519733,0.0000242669,0.0001445779,0.006889418,0.0001293492,0.001675739],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006775861,"threshold_uncertainty_score":0.002266765,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02634003500880839,"score_gpt":0.2679627058777938,"score_spread":0.2416226708689854,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}