{"id":"W3173351578","doi":"10.1016/j.bone.2021.116073","title":"Hyperkyphosis is not dependent on bone mass and quality in the mouse model of Marfan syndrome","year":2021,"lang":"en","type":"article","venue":"Bone","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Marfan syndrome; Endocrinology; Internal medicine; Osteopenia; Haploinsufficiency; Pathogenesis; Angiotensin II; Medicine; Fibrillin; Losartan; Phenotype; Receptor; Chemistry; Bone mineral; Osteoporosis; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003390621,0.00008290487,0.0001465986,0.00003181388,0.0000284057,0.00001190993,0.00009675586,0.00007583882,0.00002893223],"category_scores_gemma":[0.0001495606,0.00007096779,0.0000438085,0.00007336494,0.0000511105,0.000001827975,0.0001016538,0.0000927179,0.000004160719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001042829,"about_ca_system_score_gemma":0.00004632127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000169873,"about_ca_topic_score_gemma":0.0003406699,"domain_scores_codex":[0.9990876,0.0001273605,0.0001560493,0.0002681705,0.000209504,0.0001513245],"domain_scores_gemma":[0.9994686,0.00003018462,0.00003383049,0.0003722132,0.00006425838,0.00003094213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001088336,0.0001446226,0.002874903,0.00003417993,0.00002128812,0.00001622944,0.0001673389,0.00005068894,0.9952951,0.0002245041,0.00009875042,0.000963553],"study_design_scores_gemma":[0.0009378471,0.0001814031,0.01775064,0.00001029376,0.000008921468,0.00002236848,0.0006337308,0.0004170501,0.9792736,0.0002386157,0.0003735827,0.0001519925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970165,0.0008553326,0.0001841597,0.001064294,0.000006689516,0.0001265389,0.00007842224,0.000001887769,0.0006661313],"genre_scores_gemma":[0.9971043,0.0002961906,0.0001612068,0.0003656148,0.000005777724,0.00002046257,0.00002483177,0.00001021855,0.00201135],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01602156,"threshold_uncertainty_score":0.2893983,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04973850834990821,"score_gpt":0.3189647924956966,"score_spread":0.2692262841457884,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}